Obesity is a major health issue. Obesity started from teenagers has become a major health
concern in recent years. Intermittent fasting increases the life span. However, it is not known …

Obesity arising from excessive dietary fat intake is a risk factor for cognitive decline,
dementia and neurodegenerative diseases, including Alzheimer's disease. Here, we studied …

Time-restricted feeding ameliorates the deleterious effects of a high-fat diet on body weight
and metabolism in young adult mice. Because obesity is highly prevalent in the middle-aged …

The importance of diet and the gut-brain axis for brain health and cognitive function is
increasingly acknowledged. Dietary interventions are tested for their potential to prevent …

▪ Abstract The size and frequency of meals are fundamental aspects of nutrition that can
have profound effects on the health and longevity of laboratory animals. In humans …

Objective: Midlife obesity affects cognition and increases risk of developing dementia.
Recent data suggest that intake of the short chain fatty acid butyrate could improve memory …

Dietary restriction has been shown to have several health benefits including increased
insulin sensitivity, stress resistance, reduced morbidity, and increased life span. The …

The dual intervention point model states that body mass is controlled by upper and lower
intervention points, above and below which animals (and humans) intervene physiologically …

Feeding rodents a high-fat diet (HFD) disrupts normal behavioral rhythms, particularly meal
timing. Within the brain, mistimed feeding shifts molecular rhythms in the hippocampus and …

Results from our work in rats and others findings from human epidemiologic studies
demonstrate deficits in cognitive performance following chronic ingestion of high fat, high …