(57) ABSTRACT A method of detecting reciprocal gene translocations by employing multiple
probe sets which span the breakpoint regions and encompass regions on both sides of each …

This application claims the benefit of US Provisional Application No. 60/017,662, filed May
14, 1996. The present invention is relative to nucleic acids for demonstrating translocation …

Methods and compositions for Staining based upon nucleic acid Sequence that employ
nucleic acid probes are provided. Said methods produce Staining patterns that can be …

Probes and methods of using the probes to detect chromosomal rearrangements and/or
deletions are provided. The methods utilize probes that are free of repeat sequences to …

The invention is directed to a DNA probe set, the probe set comprising a first probe set and a
second probe set, the first probe set being sufficient in length and substantially …

This invention relates generally to methods and compositions for direct detection of specific
nucleic acid flanking sequences associated with structural chromosomal aberration …

US8187812B2 - DNA recombination junction detection - Google Patents US8187812B2 -
DNA recombination junction detection - Google Patents DNA recombination junction …

This invention relates generally to methods and composi tions for direct detection of Specific
nucleic acid flanking Sequences associated with Structural chromosomal aberra tion …

(57) ABSTRACT A novel method for detecting chromosome aberrations is disclosed. More
specifically, chromosome aberrations are detected by in situ hybridisation using at least two …

The invention relates to the field of cytogenetics and the application of genetic diagnostic
techniques in pathology and hematology. Specifically, the invention relates to nucleic acid …