Bone Loss in Inflammatory Rheumatic Musculoskeletal Disease Patients Treated With Low‐Dose Glucocorticoids and Prevention by Anti‐Osteoporosis Medications

G Adami, A Fassio, M Rossini, C Benini… - Arthritis & …, 2023 - Wiley Online Library
Objective The negative effects of glucocorticoids on bone depend on dose and treatment
duration. However, it is unclear whether a safe dose exists, especially for patients with …

Low-dose oral glucocorticoid therapy and risk of osteoporotic fractures in patients with rheumatoid arthritis: a cohort study using the Clinical Practice Research …

S Abtahi, JHM Driessen, AM Burden… - …, 2022 - academic.oup.com
Objectives Clinical trials have shown that low-dose glucocorticoid therapy in patients with
RA reduces bone loss in hands or hip, but the effect on osteoporotic fractures is not yet clear …

[HTML][HTML] Sex and age do not modify the association between glucocorticoids and bone mineral density in patients with rheumatoid arthritis: a cross-sectional study

A Palmowski, Z Boyadzhieva, SM Nielsen… - Arthritis Research & …, 2023 - Springer
Background It is unclear whether sex or age modify the association of glucocorticoid (GC)
use with reduced bone mineral density (BMD) in patients with rheumatoid arthritis (RA) …

Glucocorticoids are associated with an increased risk for vertebral fracture in patients with rheumatoid arthritis

D Kim, SK Cho, B Park, EJ Jang, SC Bae… - The Journal of …, 2018 - jrheum.org
Objective. To identify the effects of glucocorticoids (GC) on various types of fractures in
patients with rheumatoid arthritis (RA). Methods. We used the Korean National Healthcare …

Effects of glucocorticoids on osteoporosis in rheumatoid arthritis: a systematic review and meta-analysis

Y Wang, R Zhao, Z Gu, C Dong, G Guo, L Li - Osteoporosis International, 2020 - Springer
We evaluated the effects of glucocorticoids on bone mineral density (BMD), and prevalence
of osteoporosis and fracture in rheumatoid arthritis (RA) by meta-analysis. Until June 26 …

[HTML][HTML] A rational use of glucocorticoids in patients with early arthritis has a minimal impact on bone mass

M Ibañez, AM Ortiz, I Castrejón… - Arthritis research & …, 2010 - Springer
Introduction Glucocorticoid (GC)-induced osteoporosis is a frequent complication in patients
with rheumatoid arthritis. However, little information exists about the consequences of GC …

Glucocorticoid exposure and fracture risk in patients with new-onset rheumatoid arthritis

A Balasubramanian, SW Wade, RA Adler… - Osteoporosis …, 2016 - Springer
Retrospective claims analysis indicated that high levels of daily and cumulative doses of
systemic glucocorticoids were associated with elevated fracture risk in a large cohort of new …

Prevention and treatment of bone changes associated with exposure to glucocorticoids

AH Warriner, KG Saag - Current osteoporosis reports, 2013 - Springer
Rheumatologic diseases are associated with a proinflammatory state, which is thought to
lead to many of the bone changes seen in treatment-naive patients. However …

The impact of low-dose glucocorticoids on disease activity, bone mineral density, fragility fractures, and 10-year probability of fractures in patients with rheumatoid …

TT Cheng, HM Lai, SF Yu, WC Chiu… - Journal of …, 2018 - journals.sagepub.com
This study aimed to investigate the effect of low-dose glucocorticoids (LDGs) on disease
activity, bone density, and fractures in patients with rheumatoid arthritis (RA). This was an …

[PDF][PDF] Missed opportunities in physician management of glucocorticoid‐induced osteoporosis?

R Ramsey‐Goldman - Arthritis & Rheumatism, 2002 - academia.edu
Glucocorticoids, prescribed for their antiinflammatory and immunosuppressive features, are
the most common cause of secondary osteoporosis. Used to treat a variety of diseases …