European Society for Sexual Medicine consensus statement on the use of the cavernous nerve injury rodent model to study postradical prostatectomy erectile …

E Weyne, MM Ilg, OO Cakir, A Muneer… - Sexual …, 2020 - academic.oup.com
Introduction Rodent animal models are currently the most used in vivo model in translational
studies looking into the pathophysiology of erectile dysfunction after nerve-sparing radical …

Cavernous nerve injury using rodent animal models

O Canguven, A Burnett - The journal of sexual medicine, 2008 - academic.oup.com
Introduction With the advance of the “nerve sparing” technique in radical pelvic surgeries,
medically unaided rates of normal erectile function following surgery have improved. Precise …

The Cavernous Nerve Injury Rat Model: A Pictorial Essay on Post-Radical Prostatectomy Erectile Dysfunction Research

SC Latcu, D Novacescu, VB Buciu, CS Dumitru… - Life, 2023 - mdpi.com
Understanding and addressing post-radical prostatectomy (RP) erectile dysfunction (ED) is
of paramount importance for clinicians. Cavernous nerve (CN) injury rat model studies have …

Bilateral cavernous nerve crush injury in the rat model: a comparative review of pharmacologic interventions

NM Haney, HMT Nguyen, M Honda… - Sexual Medicine …, 2018 - academic.oup.com
Introduction It is common for men to develop erectile dysfunction after radical prostatectomy.
The anatomy of the rat allows the cavernous nerve (CN) to be identified, dissected, and …

The development of a rat model of erectile dysfunction after radical prostatectomy: preliminary findings

O Kaufmann, J Claro, J Cury, E Andrade… - BJU …, 2008 - Wiley Online Library
OBJECTIVE To develop a rat model of erectile dysfunction (ED) after cavernous nerve injury.
MATERIALS AND METHODS Given the great similarity between the anatomical structure of …

Long-term consequences of bilateral cavernous crush injury in normal and diabetic rats: a functional study

F Castiglione, M Albersen, S Fiorenzo… - International journal of …, 2022 - nature.com
A recent statement from the European-Society-for-Sexual-Medicine has highlighted the
limitations of using the rat model for nerve-sparing prostatectomy. The use of young rats with …

A mouse model of cavernous nerve injury-induced erectile dysfunction: functional and morphological characterization of the corpus cavernosum

HR Jin, YG Chung, WJ Kim, LW Zhang… - The Journal of …, 2010 - academic.oup.com
Introduction With the advent of genetically engineered mice, it seems important to develop a
mouse model of cavernous nerve injury (CNI). Aim To establish a mouse model of CNI …

Electrocautery‐induced cavernous nerve injury in rats that mimics radical prostatectomy in humans

LJ Song, JQ Zhu, MK Xie, YC Wang, HB Li… - BJU …, 2014 - Wiley Online Library
Objective To investigate the early and delayed effects of cavernous nerve electrocautery
injury (CNEI) in a rat model, with the expectation that this model could be used to test …

Erectile function restoration after repair of excised cavernous nerves by autologous vein graft in rats

W Hu, B Cheng, T Liu, S Li, Y Tian - The Journal of Sexual …, 2010 - academic.oup.com
ABSTRACT Introduction Cavernous nerves (CNs) injury is the main cause of erectile
dysfunction (ED) following radical prostatectomy. Its restoration remains challenging. Aim To …

An update on the current status and future prospects of erectile dysfunction following radical prostatectomy

H Asker, D Yilmaz‐Oral, CV Oztekin, S Gur - The Prostate, 2022 - Wiley Online Library
Background Radical prostatectomy (RP) and radiation treatment are standard options for
localized prostate cancer. Even though nerve‐sparing techniques have been increasingly …