[HTML][HTML] Redox imbalance in patients with heart failure and ICD/CRT-D intervention. Can it be an underappreciated and overlooked arrhythmogenic factor? A first …

J Szyller, R Antoniak, K Wadowska, I Bil-Lula… - Frontiers in …, 2023 - frontiersin.org
Introduction: Redox imbalance and oxidative stress are involved in the pathogenesis of
arrhythmias. They also play a significant role in pathogenesis of heart failure (HF). In …

[HTML][HTML] Evidence for a hyper-reductive redox in a sub-set of heart failure patients

T Sairam, AN Patel, M Subrahmanian… - Journal of Translational …, 2018 - Springer
Background Oxidative stress has been linked to heart failure (HF) in humans. Antioxidant-
based treatments are often ineffective. Therefore, we hypothesize that some of the HF …

Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications

T Münzel, T Gori, JF Keaney Jr, C Maack… - European heart …, 2015 - academic.oup.com
Systolic and diastolic myocardial dysfunction has been demonstrated to be associated with
an activation of the circulating and local renin–angiotensin–aldosterone system (RAAS), and …

The possible role of oxidative stress in heart failure and the potential of antioxidant intervention

P Korantzopoulos, D Galaris… - Medical Science …, 2003 - medscimonit.com
Heart failure (HF) is a major health problem, causing significant morbidity and mortality. Its
complex pathophysiology has not yet been fully elucidated. There is growing evidence that …

Influence of cardiac resynchronization therapy on oxidative stress markers in patients with chronic heart failure

W Krupa, M Rozwodowska, S Sielski… - Cardiology …, 2014 - journals.viamedica.pl
Background: The aim of the study was to assess changes of substances of oxidative stress
in patients treated with cardiac resynchronization therapy (CRT). Methods: The study …

Reductive stress causes pathological cardiac remodeling and diastolic dysfunction

G Shanmugam, D Wang, SS Gounder… - Antioxidants & Redox …, 2020 - liebertpub.com
Aims: Redox homeostasis is tightly controlled and regulates key cellular signaling pathways.
The cell's antioxidant response provides a natural defense against oxidative stress, but …

Oxidative stress in patients with acute heart failure

JC Charniot, N Vignat, JP Albertini… - Rejuvenation …, 2008 - liebertpub.com
Oxidative stress (OS) is a keystone in the pathology of the ischemia reperfusion sequence
(acute coronary syndromes, cardiac surgery, transplantation). In heart failure, the implication …

[HTML][HTML] Oxidative stress status increase in patients with nonischemic heart failure

M Karabacak, A Dogan, S Tayyar, HA Bas - Medical Principles and …, 2014 - karger.com
Objective: It was the aim of this study to investigate the serum oxidative stress level in
nonischemic patients with heart failure (HF). Subjects and Methods: The study included 37 …

Redox-sensitive mechanisms underlying vascular dysfunction in heart failure

J Konradi, M Mollenhauer, S Baldus… - Free radical …, 2015 - Taylor & Francis
Regardless of the progress in therapeutic drugs and devices to treat heart failure (HF) during
the last few years, the clinical outcome of this disease remains deleterious. Impaired left …

Ventricular arrhythmias following exposure of failing hearts to oxidative stress in vitro

F Brigadeau, P Gelé, C Marquie… - Journal of …, 2005 - Wiley Online Library
Introduction: There is experimental evidence that heart failure (HF) is an oxidative stress and
that HF myocytes may be damaged by oxygen‐derived free radicals. However, the …