Airflow and particle transport in the human respiratory system

C Kleinstreuer, Z Zhang - Annual review of fluid mechanics, 2010 - annualreviews.org
Airflows in the nasal cavities and oral airways are rather complex, possibly featuring a
transition to turbulent jet-like flow, recirculating flow, Dean's flow, vortical flows, large …

Modeling airflow and particle transport/deposition in pulmonary airways

C Kleinstreuer, Z Zhang, Z Li - Respiratory physiology & neurobiology, 2008 - Elsevier
A review of research papers is presented, pertinent to computer modeling of airflow as well
as nano-and micron-size particle deposition in pulmonary airway replicas. The key modeling …

Laminar airflow and nanoparticle or vapor deposition in a human nasal cavity model

H Shi, C Kleinstreuer, Z Zhang - 2006 - asmedigitalcollection.asme.org
The transport and deposition of nanoparticles, ie, dp= 1–2 nm, or equivalent vapors, in the
human nasal cavities is of interest to engineers, scientists, air-pollution regulators, and …

Airflow structures and nano-particle deposition in a human upper airway model

Z Zhang, C Kleinstreuer - Journal of computational physics, 2004 - Elsevier
Considering a human upper airway model, or equivalently complex internal flow conduits,
the transport and deposition of nano-particles in the 1–150 nm diameter range are simulated …

Effects of oral airway geometry characteristics on the diffusional deposition of inhaled nanoparticles

J Xi, PW Longest - 2008 - asmedigitalcollection.asme.org
The deposition of ultrafine aerosols in the respiratory tract presents a significant health risk
due to the increased cellular-level response that these particles may invoke. However, the …

Fluid dynamics of the human larynx and upper tracheobronchial airways

TB Martonen, Z Zhang… - Aerosol science and …, 1993 - Taylor & Francis
The deposition sites of inhaled particles must be known to (1) promote therapeutic effects of
airborne pharmacologic drugs via targeted delivery and (2) improve risk assessments of …

Comparison of micro-and nano-size particle depositions in a human upper airway model

Z Zhang, C Kleinstreuer, JF Donohue, CS Kim - Journal of aerosol science, 2005 - Elsevier
Simulation results of microparticle and nanoparticle deposition patterns, local
concentrations, and segmental averages are contrasted for a human upper airway model …

Micro-particle transport and deposition in a human oral airway model

Z Zhang, C Kleinstreuer, CS Kim - Journal of Aerosol Science, 2002 - Elsevier
Laminar-to-turbulent air flow for typical inhalation modes as well as micro-particle transport
and wall deposition in a representative human oral airway model have been simulated …

Fluid flow and particle diffusion in the human upper respiratory system

G Yu, Z Zhang, R Lessmann - Aerosol science and technology, 1998 - Taylor & Francis
Airflow patterns within the human upper airways, including nasal airway, oral airway,
laryngeal airway, and the first two generations of tracheobronchial airway, are investigated …

Computational fluid dynamics simulation of airflow and aerosol deposition in human lungs

N Nowak, PP Kakade, AV Annapragada - Annals of biomedical …, 2003 - Springer
Computational fluid dynamics (CFD) simulations of airflow and particle deposition in
geometries representing the human tracheobronchial tree were conducted. Two geometries …