Recovery from influenza virus infection is dependent on T cell functions which can be
provided either by CD8 or CD4 T cells. To identify the functions involved in recovery …

Recovery from influenza virus infection has long been known to require an intact T‐cell
compartment. More recent studies revealed that CD8 and CD4Tcells can promote recovery …

The primary CD8+ T-cell response protected most B-cell-deficient μMT mice against
intranasal infection with the HKx31 influenza A virus. Prior exposure did not prevent …

T lymphocytes play a primary role in recovery from viral infections and in antiviral immunity.
Although viral-specific CD8+ and CD4+ T cells have been shown to be able to lyse virally …

Previous studies have indicated that B cells make a significant contribution to the resolution
of influenza virus infection. To determine how B cells participate in the control of the …

The notion that MHC class I-restricted CD8+ T (Tc) cells are capable of resolving
autonomously infections with influenza virus is based largely on studies testing virus strains …

Optimal expansion of influenza virus nucleoprotein (DbNP366)-specific CD8+ T cells
following respiratory challenge of naive Ig−/− μMT mice was found to require CD4+ T-cell …

The primary influenza A virus-specific CD8+-T-cell responses measured by tetramer staining
of spleen, lymph node, and bronchoalveolar lavage (BAL) lymphocyte populations were …

To investigate the role of CD8+ T lymphocytes in recovery from influenza pneumonia, we
used transgenic mice either homozygous (-/-) or heterozygous (+/-) for beta 2-microglobulin …

The experiments described establish that CD4+ T-cell-dependent effector mechanisms can
eliminate an H3N2 influenza A virus from lung cells that are unable to express class II major …