A “One-Step” Strategy for the Global Characterization of Core-Fucosylated Glycoproteome

Y Wang, R Yuan, B Liang, J Zhang, Q Wen, H Chen… - JACS Au, 2024 - ACS Publications
Core fucosylation, a special type of N-linked glycosylation, is important in tumor proliferation,
invasion, metastatic potential, and therapy resistance. However, the core-fucosylated …

Improvement of core-fucosylated glycoproteome coverage via alternating HCD and ETD fragmentation

C Ma, J Qu, X Li, X Zhao, L Li, C Xiao, G Edmunds… - Journal of …, 2016 - Elsevier
Core-fucosylation (CF) plays important roles in regulating biological processes in
eukaryotes. Alterations of CF-glycosites or CF-glycans in bodily fluids correlate with cancer …

Quantitative Characterization of Protein N-Linked Core-Fucosylation by an Efficient Glycan Truncation Strategy

X Guo, X Liu, C Zhao, Z Fang, D Sun, F Tang… - Analytical …, 2024 - ACS Publications
Dysregulation of protein core-fucosylation plays a pivotal role in the onset, progression, and
immunosuppression of cancer. However, analyzing core-fucosylation, especially the …

Large-scale identification of core-fucosylated glycopeptide sites in pancreatic cancer serum using mass spectrometry

Z Tan, H Yin, S Nie, Z Lin, J Zhu, MT Ruffin… - Journal of proteome …, 2015 - ACS Publications
Glycosylation has significant effects on protein function and cell metastasis, which are
important in cancer progression. It is of great interest to identify site-specific glycosylation in …

Characterization of core fucosylation via sequential enzymatic treatments of intact glycopeptides and mass spectrometry analysis

L Cao, TM Lih, Y Hu, M Schnaubelt, SY Chen… - Nature …, 2022 - nature.com
Core fucosylation of N-linked glycoproteins has been linked to the functions of glycoproteins
in physiological and pathological processes. However, quantitative characterization of core …

A precise approach in large scale core-fucosylated glycoprotein identification with low-and high-normalized collision energy

C Ma, Q Zhang, J Qu, X Zhao, X Li, Y Liu, PG Wang - Journal of proteomics, 2015 - Elsevier
The core fucosylation (CF) of N-glycoproteins plays important roles in regulating protein
functions during biological development, and it has also been shown to be up-regulated in …

Identification of core-fucosylated glycoproteome in human plasma

Q Cao, Q Zhao, X Qian, W Ying - Serum/Plasma Proteomics: Methods and …, 2017 - Springer
The core-fucosylated (CF) glycoproteins are widely distributed in mammalian tissues and
regulated under pathological conditions, especially in cancer progression. The Food and …

A Strategy for Precise and Large Scale Identification of Core Fucosylated Glycoproteins* S

W Jia, Z Lu, Y Fu, HP Wang, LH Wang, H Chi… - Molecular & Cellular …, 2009 - ASBMB
Core fucosylation (CF) patterns of some glycoproteins are more sensitive and specific than
evaluation of their total respective protein levels for diagnosis of many diseases, such as …

A Sensitive and Reversible Labeling Strategy Enables Global Mapping of the Core‐Fucosylated Glycoproteome on Cell Surfaces

Y Tian, Y Wang, H Yin, Y Luo, F Wei… - Angewandte …, 2022 - Wiley Online Library
Core fucosylation, the attachment of α1, 6‐fucose to the innermost N‐acetylglucosamine
(GlcNAc) residue of N‐glycans, has a strong relationship with tumor growth, invasion …

Development of an AlphaLISA assay to quantify serum core-fucosylated E-cadherin as a metastatic lung adenocarcinoma biomarker

CL Wen, KY Chen, CT Chen, JG Chuang, PC Yang… - Journal of …, 2012 - Elsevier
Lung cancer is the leading cause of cancer-associated deaths worldwide. Non-small cell
lung cancer is a heterogeneous condition with variability in prognosis and in individual …