Polo-like kinase 1 (Plk1) is a key regulator of cell division in eukaryotic cells. New
techniques, including the application of small-molecule inhibitors, have greatly expanded …

Polo-like kinase 1 (PLK1) is a key regulator of eukaryotic cell division. During mitosis,
dynamic regulation of PLK1 is crucial for its roles in centrosome maturation, spindle …

Polo-like kinase 1 (Plk1) is a key regulator of mitotic progression and cell division in
eukaryotes. It is highly expressed in tumor cells and considered a potential target for cancer …

Polo-like kinase 1 (Plk1) has multiple important functions during M-phase progression. In
addition to a catalytic domain, Plk1 possesses a phosphopeptide-binding motif, the polo-box …

Polo-like kinase 1 (Plk1) functions as a key regulator of mitotic events by phosphorylating
substrate proteins on centrosomes, kinetochores, the mitotic spindle, and the midbody …

During cell division, duplicated genetic material is separated into two distinct daughter cells.
This process is essential for initial tissue formation during development and to maintain …

Polo-like kinase (Plk) 1 executes several essential functions to promote cell division. These
functions range from centrosome maturation in late G2 phase to the regulation of …

Polo-like kinases (Plks) are increasingly recognized as key regulators of mitosis, meiosis
and cytokinesis. In agreement with a broad range of proposed functions during cell division …

Polo-like kinase-1 (Plk1) performs multiple essential functions during the cell cycle. Here we
show that human Plk1-deficient cells are unable to separate their centrosomes, fail to form a …

Polo-like kinases regulate many aspects of mitotic and meiotic progression from yeast to
man. In early mitosis, mammalian Polo-like kinase 1 (Plk1) controls centrosome maturation …