Platelet ageing is an area of research which has gained much interest in recent years.
Newly formed platelets, often referred to as reticulated platelets, young platelets or immature …

Research into the natural aging process of platelets has garnered much research interest in
recent years, and there have long been associations drawn between the proportion of newly …

The proportion of young platelets, also known as newly formed or reticulated, within the
overall platelet population has been clinically correlated with adverse cardiovascular …

Aging is associated with an increased incidence of cardiovascular disease and thrombosis.
Platelets play a major role in maintaining hemostasis and in thrombus formation, making …

Although there have been advances dissecting the molecular mechanisms regarding aging-
related changes in platelets, many knowledge gaps still remain. Studies filling these gaps …

Platelet survival can be determined with considerable precision using radioisotopic
methodologies; however, complications associated with these techniques still catalyze the …

After the intravenous infusion of N-hydroxysuccinimido biotin into dogs, 80.6%+/-9.7%(n= 5)
of platelets were covalently labeled with biotin. The in vivo survival of the biotinylated …

The factors controlling the lifespan of platelets both in vivo and in vitro are poorly
understood. What is known is that platelet aging in vivo leads to a reduction in the platelets' …

Background Platelets circulate in the blood of healthy individuals for approximately 7–10
days regulated by finely balanced processes of production and destruction. As platelets are …

There are clear age-related changes in platelet count and function, driven by changes in
hematopoietic tissue, the composition of the blood and vascular health. Platelet count …