Mesenchymal stem/stromal cells in cancer therapy

T Lan, M Luo, X Wei - Journal of Hematology & Oncology, 2021 - Springer
The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone
marrow in 1976, have been identified in nearly all tissues of human body now. The …

[HTML][HTML] Mesenchymal stem/stromal cells: developmental origin, tumorigenesis and translational cancer therapeutics

C Li, H Zhao, B Wang - Translational oncology, 2021 - Elsevier
While a large and growing body of research has demonstrated that mesenchymal
stem/stromal cells (MSCs) play a dual role in tumor growth and inhibition, studies exploring …

Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

Y Shi, L Du, L Lin, Y Wang - Nature reviews Drug discovery, 2017 - nature.com
Mesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), exist in many
tissues and are known to actively migrate to sites of tissue injury, where they participate in …

The dual role of mesenchymal stem cells in cancer pathophysiology: pro-tumorigenic effects versus therapeutic potential

Y Slama, F Ah-Pine, M Khettab, A Arcambal… - International Journal of …, 2023 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are multipotent cells involved in numerous
physiological events, including organogenesis, the maintenance of tissue homeostasis …

Mesenchymal stem cells and cancer: clinical challenges and opportunities

W Lin, L Huang, Y Li, B Fang, G Li… - BioMed research …, 2019 - Wiley Online Library
Stem cell‐based therapies exhibit profound therapeutic potential for treating various human
diseases, including cancer. Among the cell types that can be used for this purpose …

Concise review: adult multipotent stromal cells and cancer: risk or benefit?

G Lazennec, C Jorgensen - Stem cells, 2008 - academic.oup.com
This review focuses on the interaction between multipotent stromal cells (MSCs) and
carcinoma and the possible use of MSCs in cell-based anticancer therapies. MSCs are …

Review of mesenchymal stem cells and tumors: executioner or coconspirator?

B Feng, L Chen - Cancer Biotherapy and Radiopharmaceuticals, 2009 - liebertpub.com
Mesenchymal stem cells (MSCs) are a versatile group of nonhematopoietic stem cells with
high potency of proliferation and pluripotency of differentiation. Endogenous MSCs circulate …

Mesenchymal stem cell signaling in cancer progression

A Torsvik, R Bjerkvig - Cancer treatment reviews, 2013 - Elsevier
Mesenchymal (multipotent) stem/stromal cells (MSCs) may affect cancer progression
through a number of secreted factors triggering activation of various cell signaling pathways …

Double‐edged sword of mesenchymal stem cells: cancer‐promoting versus therapeutic potential

HY Lee, IS Hong - Cancer science, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) derived from adipose tissue, bone marrow, cord blood, and
other tissues, have recently attracted much attention as potential therapeutic agents in …

Mesenchymal stem cells in suppression or progression of hematologic malignancy: current status and challenges

MW Lee, S Ryu, DS Kim, JW Lee, KW Sung, HH Koo… - Leukemia, 2019 - nature.com
Mesenchymal stem cells (MSCs) are known for being multi-potent. However, they also
possess anticancer properties, which has prompted efforts to adapt MSCs for anticancer …