Genome mining has become a key technology to exploit natural product diversity. Although
initially performed on a single-genome basis, the process is now being scaled up to mine …

The pairing of analytical chemistry with genomic techniques represents a new wave in
natural product chemistry. With an increase in the availability of sequencing and assembly of …

With an ever-increasing amount of (meta) genomic data being deposited in sequence
databases,(meta) genome mining for natural product biosynthetic pathways occupies a …

Natural products (NPs), or specialized metabolites, are important for medicine and
agriculture alike, and for the fitness of the organisms that produce them. NP genome-mining …

Background Genome mining for biosynthetic gene clusters (BGCs) has become an integral
part of natural product discovery. The> 200,000 microbial genomes now publicly available …

Covering: 2016 to 2021 With genetic information available for hundreds of thousands of
organisms in publicly accessible databases, scientists have an unprecedented opportunity …

Actinobacteria encode a wealth of natural product biosynthetic gene clusters, whose
systematic study is complicated by numerous repetitive motifs. By combining several metrics …

Summary Environmental Surveyor of Natural Product Diversity (eSNaPD) is a web-based
bioinformatics and data aggregation platform that aids in the discovery of gene clusters …

Starting with the earliest Streptomyces genome sequences, the promise of natural product
genome mining has been captivating: genomics and bioinformatics would transform …

The advent of the genomic era has opened up enormous possibilities for the discovery of
new natural products. Also known as specialized metabolites, these compounds produced …