The tumor microenvironment (TME) plays key roles in promoting disease progression in the
aggressive triple-negative subtype of breast cancer (TNBC; Basal/Basal-like). Here, we took …

Stromal cells and pro-inflammatory cytokines play key roles in promoting the
aggressiveness of triple-negative breast cancers (TNBC; Basal/Basal-like). In our previous …

Purpose: The tumor microenvironment has a profound impact on prognosis and
immunotherapy. However, the landscape of the triple-negative breast cancer (TNBC) …

Triple negative breast cancer (TNBC) as a metastatic disease is currently incurable. Reliable
and reproducible methods for testing drugs against metastasis are not available. Stromal …

Introduction Breast cancer progression is promoted by stromal cells that populate the
tumors, including cancer-associated fibroblasts (CAFs) and mesenchymal stem/stromal cells …

Background: The impact of the immune landscape of the microenvironment on cancer
progression is not well understood for triple-negative breast cancer (TNBC). We, therefore …

Tumor associated neutrophils (TANs) are frequently detected in triple-negative breast
cancer (TNBC). Recent studies also reveal the importance of neutrophils in promoting tumor …

Triple-negative (TN) breast cancers (ER− PR− HER2−) are highly metastatic and associated
with poor prognosis. Within this subtype, invasive, stroma-rich tumours with infiltration of …

Background Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast
cancer with poor prognosis and limited treatment. As a major component of the tumor …

The tumour stroma regulates nearly all stages of carcinogenesis. Stromal heterogeneity in
human triple‐negative breast cancers (TNBCs) remains poorly understood, limiting the …