Tumor angiogenesis is one of the hallmarks of tumor progression and is essential for
invasiveness and metastasis. Myeloid inflammatory cells, such as immature myeloid …

Angiogenesis, or generation of new blood vessels from pre-existing vessels, is an integral
part of many physiological or pathological processes, including tumor growth. Physiological …

The angiogenic process involves several cell types and mediators, which interact to
establish a specific microenvironment suitable for the formation of new capillaries from pre …

The tumor microenvironment consists of tumor, immune, stromal, and inflammatory cells
which produce cytokines, growth factors, and adhesion molecules that promote tumor …

Inflammatory mediators in tumor microenvironment influence cancer occurrence, growth and
metastasis through complex signaling networks. Excessive inflammation is closely …

Tumor progression relies on the ability of cancer cells to effectively invade surrounding
tissues and propagate. Among the many mechanisms that contribute to tumor progression is …

In this study, we assessed the involvement of IL-1β in early angiogenic responses induced
by malignant cells using Matrigel plugs supplemented with B16 melanoma cells. We found …

Abstract Interleukin-1 (IL-1) includes a family of closely related genes; the two major
agonistic proteins, IL-1α and IL-1β, are pleiotropic and affect mainly inflammation, immunity …

The cytokine IL6 has a number of tumor-promoting activities in human and experimental
cancers, but its potential as an angiogenic agent has not been fully investigated. Here, we …

In-depth knowledge of cancer molecular and cellular mechanisms have revealed a strong
regulation of cancer development and progression by the inflammation which orchestrates …