Cholesterol, the most important sterol in mammals, helps maintain plasma membrane fluidity
and is a precursor of bile acids, oxysterols, and steroid hormones. Cholesterol in the body is …

Inflammation represents the driving feature of many diseases, including atherosclerosis,
cancer, autoimmunity and infections. It is now established that metabolic processes shape a …

The immune system protects the body against harm by inducing inflammation. During the
immune response, cells of the immune system get activated, divided and differentiated in …

Atherosclerosis: the interplay between lipids and immune cel... : Current Opinion in Lipidology
Atherosclerosis: the interplay between lipids and immune cells : Current Opinion in Lipidology …

Cardiovascular disease (CVD) continues to be a leading cause of death worldwide with
atherosclerosis being the major underlying pathology. The interplay between lipids and …

Abstract Purpose of Review Atherosclerosis is an inflammatory disorder of the arterial wall,
in which several players contribute to the onset and progression of the disease. Besides the …

Cholesterol has typically been considered an exogenous, disease-related factor in
immunity; however, recent literature suggests that a paradigm shift is in order. Sterols are …

Hypercholesterolaemia leads to cholesterol accumulation in macrophages and other
immune cells, which promotes inflammatory responses, including augmentation of Toll-like …

Mechanisms of lipid homeostasis and its impairment are of crucial importance for
atherogenesis, and their understanding is necessary for successful development of new …

Cholesterol is an essential molecule that exerts pleiotropic actions. Although its presence is
vital to the cell, its excess can be harmful and, therefore, sustaining cholesterol homeostasis …