Airflow limitation with intractable progressive mechanisms is the main disease feature of
chronic obstructive pulmonary disease (COPD). The pathological process of airflow …

Chronic obstructive pulmonary disease (COPD) is a disease state in which chronic
inflammation drives irreversible airway remodeling and airspace destruction, leading to …

In the past decades, apoptosis has been the most well-studied regulated cell death (RCD)
that has essential functions in tissue homeostasis throughout life. However, a novel form of …

Rationale: Necroptosis, mediated by RIPK3 (receptor-interacting protein kinase 3) and
MLKL (mixed lineage kinase domain-like), is a form of regulated necrosis that can drive …

Cell death is an essential process in multicellular organisms and has important roles in
human physiology and disease. It can be broadly classified as either programmed, such as …

Chronic obstructive pulmonary disease (COPD) is a cigarette smoking-related disorder
characterized by chronic inflammation of the airways and progressive destruction of lung …

Background/Aims: Necroptosis, a form of programmed necrosis, is involved in the pathologic
process of several kinds of pulmonary diseases. However, the role of necroptosis in …

Although the major sites of airflow limitation in patients with COPD are most likely the
peripheral airways, lesions in both the peripheral airways and the lung parenchyma …

By regulating the cell number and eliminating harmful cells, programmed cell death plays a
critical role in development, homeostasis, and disease. While apoptosis is a recognized form …

Chronic obstructive pulmonary disease (COPD) is a highly prevalent airway disease
characterized by an abnormal inflammatory response of the lungs to noxious particles and …