Metabolomics and type 2 diabetes risk: an updated systematic review and meta-analysis of prospective cohort studies

J Morze, C Wittenbecher, L Schwingshackl… - Diabetes …, 2022 - Am Diabetes Assoc
BACKGROUND Due to the rapidly increasing availability of metabolomics data in
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …

Metabolomics in prediabetes and diabetes: a systematic review and meta-analysis

M Guasch-Ferré, A Hruby, E Toledo, CB Clish… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE To conduct a systematic review of cross-sectional and prospective human
studies evaluating metabolite markers identified using high-throughput metabolomics …

Serum metabolomic profile of incident diabetes

CM Rebholz, B Yu, Z Zheng, P Chang, A Tin, A Köttgen… - Diabetologia, 2018 - Springer
Aims/hypothesis Metabolomic profiling offers the potential to reveal metabolic pathways
relevant to the pathophysiology of diabetes and improve diabetes risk prediction. Methods …

Metabolomics signatures in type 2 diabetes: a systematic review and integrative analysis

Y Sun, HY Gao, ZY Fan, Y He… - The Journal of Clinical …, 2020 - academic.oup.com
Objective Metabolic signatures have emerged as valuable signaling molecules in the
biochemical process of type 2 diabetes (T2D). To summarize and identify metabolic …

Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach

A Floegel, N Stefan, Z Yu, K Mühlenbruch, D Drogan… - Diabetes, 2013 - Am Diabetes Assoc
Metabolomic discovery of biomarkers of type 2 diabetes (T2D) risk may reveal etiological
pathways and help to identify individuals at risk for disease. We prospectively investigated …

Plasma metabolomics identified novel metabolites associated with risk of type 2 diabetes in two prospective cohorts of Chinese adults

G Qiu, Y Zheng, H Wang, J Sun, H Ma… - International journal …, 2016 - academic.oup.com
Background: Metabolomics studies in Caucasians have identified a number of novel
metabolites in association with the risk of type 2 diabetes (T2D). However, few prospective …

Metabolic signatures and risk of type 2 diabetes in a Chinese population: an untargeted metabolomics study using both LC-MS and GC-MS

Y Lu, Y Wang, CN Ong, T Subramaniam, HW Choi… - Diabetologia, 2016 - Springer
Aims/hypothesis Metabolomics has provided new insight into diabetes risk assessment. In
this study we characterised the human serum metabolic profiles of participants in the …

Plasma metabolomic profiles in association with type 2 diabetes risk and prevalence in Chinese adults

D Yu, SC Moore, CE Matthews, YB Xiang, X Zhang… - Metabolomics, 2016 - Springer
Metabolomic studies have identified several metabolites associated with type 2 diabetes
(T2D) in populations of European ancestry. East Asians, a population of particular …

Untargeted metabolic profiling identifies altered serum metabolites of type 2 diabetes mellitus in a prospective, nested case control study

D Drogan, WB Dunn, W Lin, B Buijsse… - Clinical …, 2015 - academic.oup.com
BACKGROUND Application of metabolite profiling could expand the etiological knowledge
of type 2 diabetes mellitus (T2D). However, few prospective studies apply broad untargeted …

Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach

C Menni, E Fauman, I Erte, JRB Perry… - Diabetes, 2013 - Am Diabetes Assoc
Using a nontargeted metabolomics approach of 447 fasting plasma metabolites, we
searched for novel molecular markers that arise before and after hyperglycemia in a large …