[HTML][HTML] Depression and anxiety in association with polypharmacy in patients with multiple sclerosis

J Baldt, N Frahm, M Hecker, B Streckenbach… - Journal of Clinical …, 2023 - mdpi.com
Polypharmacy (intake of≥ 5 drugs) is an important issue for patients with chronic diseases
such as multiple sclerosis (MS). We aimed to assess the prevalence of polypharmacy with …

[HTML][HTML] Multi-drug use among patients with multiple sclerosis: A cross-sectional study of associations to clinicodemographic factors

N Frahm, M Hecker, UK Zettl - Scientific Reports, 2019 - nature.com
Multiple sclerosis (MS) is the most prevalent immune-mediated disease affecting the central
nervous system. A treatment strategy with multiple therapies is a frequent clinical scenario …

Polypharmacy among patients with multiple sclerosis: a qualitative systematic review

N Frahm, M Hecker, UK Zettl - Expert Opinion on Drug Safety, 2020 - Taylor & Francis
Objectives: The consequences of polypharmacy (intake of≥ 5 drugs) are diverse, including
drug interactions, rising costs and side effects. Risk groups for polypharmacy are …

Polypharmacy and multiple sclerosis: A population-based study

A Chertcoff, HS Ng, F Zhu, Y Zhao… - Multiple Sclerosis …, 2023 - journals.sagepub.com
Background: Little is known about polypharmacy and multiple sclerosis (MS). Objectives: To
estimate polypharmacy prevalence in a population-based MS cohort and compare persons …

[HTML][HTML] Polypharmacy in patients with multiple sclerosis: a gender-specific analysis

N Frahm, M Hecker, UK Zettl - Biology of sex Differences, 2019 - Springer
Background Multiple sclerosis (MS) affects about three times more women than men. Due to
variable MS courses, multiple therapies are necessary in clinical practice. Objective We …

[HTML][HTML] Polypharmacy in outpatients with relapsing-remitting multiple sclerosis: A single-center study

N Frahm, M Hecker, UK Zettl - PLoS One, 2019 - journals.plos.org
Background Multiple sclerosis (MS) is an immune-mediated disease of the central nervous
system. Given the chronic and heterogenous nature of the disease, treatment with various …

[HTML][HTML] Polypharmacy in patients with multiple sclerosis and the impact on levels of care and therapy units

F Brüggemann, S Gross, M Süße, P Hok… - Frontiers in …, 2023 - frontiersin.org
Background The aim of this study was to examine the societal costs of polypharmacy in
patients with multiple sclerosis (MS). We therefore focused on the association between the …

Psychiatric co-morbidity in multiple sclerosis: The risk of depression and anxiety before and after MS diagnosis

H Hoang, B Laursen, EN Stenager… - Multiple Sclerosis …, 2016 - journals.sagepub.com
Background: Studies of depression and anxiety in multiple sclerosis (MS) patients have
reported higher rates in MS patients than the general population. Objective: To estimate the …

Antiepileptic and antidepressive polypharmacy in patients with multiple sclerosis

GAG Beiske, T Holmøy, AG Beiske… - Multiple Sclerosis …, 2015 - Wiley Online Library
Objective. Patients with multiple sclerosis (MS) are often suffering from neuropathic pain.
Antiepileptic drugs (AEDs) and tricyclic antidepressants (TCAs) are commonly used and are …

Polypharmacy in multiple sclerosis: prevalence, risks, and mitigation strategies

WD Chapman, MC Herink, MH Cameron… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review Polypharmacy, the use of≥ 5 medications, is common in people
with multiple sclerosis and is associated with negative outcomes. The use of multiple …