Amlodipine: effective for treatment of mild to moderate essential hypertension and left ventricular hypertrophy

IF Islim, RD Watson, HNC Ihenacho, M Ebanks… - Cardiology, 2001 - karger.com
This was a 20-week, open-label, uncontrolled clinical investigation of the long-acting
calcium antagonist amlodipine in 33 male or female patients with essential hypertension …

The effects of amlodipine on left ventricular mass and diastolic function in concentric and eccentric left ventricular hypertrophy

AS Fak, M Okucu, H Tezcan… - Journal of …, 1996 - journals.sagepub.com
Background: The effects of the antihypertensive therapy with amlodipine (5-10 mg/day) on
left ventricular mass and diastolic function were examined in 30 mild to moderate essential …

Double-blind evaluation of the dose-response relationship of amlodipine in essential hypertension

JL Mehta, LM Lopez, ND Vlachakis, AH Gradman… - American heart …, 1993 - Elsevier
To determine the dose-response efficacy of once-daily administration of placebo or a new
long-acting calcium channel blocker amlodipine in patients with mild to moderate …

Effect of amlodipine on left ventricular mass in the Amlodipine Cardiovascular Community Trial

RA Kloner, JR Sowers, GF DiBona… - Journal of …, 1995 - journals.lww.com
As part of the Amlodipine Cardiovascular Community Trial (ACCT), which was a large
multicenter study designed to assess the effects of the calcium channel blocker amlodipine …

Effects of enalapril and amlodipine on left ventricular hypertrophy and function in essential hypertension

M Picca, J Bisceglia, A Zocca, G Pelosi - Clinical drug investigation, 1997 - Springer
In an 18-month randomised single-blind trial, M-mode and Doppler echocardiography were
used to compare the effects of enalapril (10 to 20 mg/day) and amlodipine (5 to 10 mg/day) …

One-year antihypertensive treatment with amlodipine: effects on 24-hour blood pressure and left ventricular anatomy and function.

M Bignotti, AM Grandi, G Gaudio, L Guasti… - Acta …, 1995 - europepmc.org
Using digitized M-mode echocardiograms and 24-hour noninvasive ambulatory blood
pressure monitoring, we evaluated the effects of 1 year treatment with amlodipine on left …

A randomized placebo-controlled comparison of amlodipine and atenolol in mild to moderate systemic hypertension

WH Frishman, R Brobyn, RD Brown… - Journal of …, 1988 - journals.lww.com
Amlodipine, a new long-acting dihydropyridine calcium antagonist, was compared with
placebo and atenolol in 125 patients with mild to moderate systemic hypertension [supine …

The efficacy and safety of amlodipine in the treatment of mild and moderate essential hypertension in general practice

J Varrone - Journal of Cardiovascular Pharmacology, 1991 - journals.lww.com
The antihypertensive efficacy and safety of amlodipine was evaluated in an open,
multicenter general practice study. Hypertensive patients with sitting diastolic blood pressure …

A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure in hypertensive patients

WJ Mroczek, JF Burris, KS Allenby - Journal of Cardiovascular …, 1988 - journals.lww.com
Amlodipine is a new long-acting calcium antagonist that has a long half-life and appears to
be suitable for once-daily administration. A double-blind, randomized, parallel, placebo …

Comparison of the effects of amlodipine and diltiazem on 24-hour blood pressure, plasma catecholamines, and left ventricular mass

FHH Leenen, A Fourney - The American journal of cardiology, 1996 - Elsevier
In 30 patients with mild to moderate essential hypertension and high-normal left ventricular
(LV) mass, the effects of treatment for 6 months with amlodipine (5 to 10 mg every morning) …