The risk assessment of chemical carcinogens is one major task in toxicology. Even though
exposure has been mitigated effectively during the last decades, low levels of carcinogenic …

The present paper examines the particular difficulties presented by low levels of food-borne
DNA-reactive genotoxic carcinogens, some of which may be difficult to eliminate completely …

Existing systems of classification of carcinogens are a matter of discussion, world-wide.
There is agreement that it should be distinguished between genotoxic and non-genotoxic …

While scientific knowledge of the potential health significance of chemical exposures has
grown, experimental methods for predicting the carcinogenicity of environmental agents …

Specific genotoxic events such as gene mutations and/or chromosome damage are
considered hallmarks of cancer. The genotoxicity testing battery enables relatively simple …

Exposure to chemical agents is an inevitable consequence of modern society; some of these
agents are hazardous to human health. The effects of chemical carcinogens are of great …

The carcinogens to which humans are exposed are normally in the form of complex
mixtures, and much effort has gone into determining the nature of the most significant …

This is the second of two reports from the International Workshops on Genotoxicity Testing
(IWGT) Working Group on Quantitative Approaches to Genetic Toxicology Risk Assessment …

The European Food Safety Authority (EFSA) and the World Health Organization (WHO), with
the support of the International Life Sciences Institute, European Branch (ILSI Europe) …

Recent advances in genetic toxicity (mutagenicity) testing methods and in approaches to
performing risk assessment are prompting a renewed effort to harmonize genotoxicity risk …