A prophage encoded ribosomal RNA methyltransferase regulates the virulence of Shiga-toxin-producing Escherichia coli (STEC)

C Gong, D Chakraborty, GB Koudelka - Nucleic Acids Research, 2024 - academic.oup.com
Shiga toxin (Stx) released by Shiga toxin producing Escherichia coli (STEC) causes life-
threatening illness. Its production and release require induction of Stx-encoding prophage …

Shiga-toxin-converting bacteriophages

H Schmidt - Research in microbiology, 2001 - Elsevier
Shiga toxins (Stx) comprise a family of potent cytotoxins that are involved in severe human
disease. Stx are mainly produced by Escherichia coli isolated from human and nonhuman …

Molecular mechanisms governing “hair-trigger” induction of shiga toxin-encoding prophages

D Chakraborty, E Clark, SA Mauro, GB Koudelka - Viruses, 2018 - mdpi.com
Shiga toxin (Stx)-encoding E. coli (STEC) strains are responsible for sporadic outbreaks of
food poisoning dating to 1982, when the first STEC strain, E. coli O157: H7, was isolated …

The CI Repressors of Shiga Toxin-Converting Prophages Are Involved in Coinfection of Escherichia coli Strains, Which Causes a Down Regulation in the Production …

R Serra-Moreno, J Jofre, M Muniesa - Journal of bacteriology, 2008 - Am Soc Microbiol
Shiga toxins (Stx) are the main virulence factors associated with a form of Escherichia coli
known as Shiga toxin-producing E. coli (STEC). They are encoded in temperate lambdoid …

Complete Genome Sequence of a Shiga Toxin-Converting Bacteriophage, Escherichia Phage Lys12581Vzw, Induced from an Outbreak Shiga Toxin-Producing …

Y Zhang, YT Liao, A Salvador, X Sun… - Microbiology Resource …, 2019 - Am Soc Microbiol
ABSTRACT Although numerous Shiga toxin (Stx)-producing Escherichia coli (STEC) strains
have been sequenced, genomic information on Stx-converting phages, highly related to the …

Role for a Phage Promoter in Shiga Toxin 2 Expression from a Pathogenic Escherichia coliStrain

PL Wagner, MN Neely, X Zhang… - Journal of …, 2001 - Am Soc Microbiol
Shiga toxins (Stxs), encoded by the stxA and stxB genes, are important contributors to the
virulence of Escherichia coli O157: H7 and other Stx-producing E. coli (STEC) strains. The …

Dam Methyltransferase Is Required for Stable Lysogeny of the Shiga Toxin (Stx2)-Encoding Bacteriophage 933W of Enterohemorrhagic Escherichia coli O157:H7

KC Murphy, JM Ritchie, MK Waldor… - Journal of …, 2008 - Am Soc Microbiol
ABSTRACT Shiga toxin 2 (Stx2), one of the principal virulence factors of enterohemorrhagic
Escherichia coli, is encoded by 933W, a lambda-like prophage. 933W prophage induction …

Comparative Genomics and Characterization of the Late Promoter pR' from Shiga Toxin Prophages in Escherichia coli

LX Zhang, DJ Simpson, LM McMullen, MG Gänzle - Viruses, 2018 - mdpi.com
Shiga-toxin producing Escherichia coli (STEC) causes human illness ranging from mild
diarrhea to death. The bacteriophage encoded stx genes are located in the late transcription …

Bacteriophage control of Shiga toxin 1 production and release by Escherichia coli

PL Wagner, J Livny, MN Neely… - Molecular …, 2002 - Wiley Online Library
The stx genes of many Shiga toxin‐encoding Escherichia coli (STEC) strains are encoded
by prophages of the λ bacteriophage family. In the genome of the Stx1‐encoding phage H …

Impact of Shiga-toxin encoding gene transduction from O80:H2 Shiga toxigenic Escherichia coli (STEC) on non-STEC strains

A Habets, C Antoine, J Wagemans, M Vermeersch… - Scientific Reports, 2022 - nature.com
Shiga toxin-producing Escherichia coli (STEC) are major foodborne pathogens that cause
human diseases ranging from diarrhea to life-threatening complications including hemolytic …