Background Hypertension is a leading cause of cardiovascular disease, stroke, and death. It
affects a substantial proportion of the population worldwide, and remains underdiagnosed …

Hypertension is a common comorbidity in patients with heart failure and most drugs that
have demonstrated to improve prognosis in this population have the potential to reduce …

Hypertension is a leading cause of heart failure and other cardiovascular diseases. Its role
in the pathogenesis of heart failure with reduced ejection fraction (HFrEF) differs from that in …

Objectives: This study aimed to assess the relationship between on-treatment blood
pressure (BP) and clinical outcomes of patients with heart failure (HF). Background: Lower …

BACKGROUND: The association between low blood pressure and prognosis in the general
population has been controversial, with some reports suggesting an increased mortality for …

In the Systolic Blood Pressure Intervention Trial (SPRINT), intensive blood pressure (BP)
lowering was associated with significant reduction in composite cardiovascular (CV) …

Background: Although higher blood pressures are generally recognised to be an adverse
prognostic marker in risk assessment of cardiology patients, its relationship to risk in chronic …

Hypertension has not always been recognized as a harbinger of cardiovascular
complications and premature death. Only 70 years ago, hypertension was considered the …

Background—Acute decompensated heart failure (ADHF) was a frequent common outcome
in SPRINT (Systolic Blood Pressure Intervention Trial). We examined whether there was …

Aims Current guidelines of hypertensive management recommend upper limits for systolic
(SBP) and diastolic blood pressure (DBP). J-curve associations of BP with risk exist for some …