PARP1 rs1136410 (A/G) polymorphism is associated with early age of onset of gallbladder cancer

K Anjali, D Singh, P Kumar, T Kumar… - European Journal of …, 2022 - journals.lww.com
Objectives Evaluation of the association of PARP1 rs1136410 (A/G) polymorphism with
gallbladder cancer susceptibility and its prognosis in the Indian population of eastern Uttar …

Association of haplotype and linkage disequilibrium of PARP1 polymorphisms rs1136410, rs1805405 and rs3219088 with gallbladder cancer

K Anjali, T Kumar, AG Kar, P Kumar, G Narayan… - Digestive and Liver …, 2023 - Elsevier
Background Previously, we have reported that PARP1 rs1136410 is significantly associated
with increased the risk of gallbladder cancer. Aim We aimed to investigate the association of …

[HTML][HTML] PARP-1 Val762Ala Polymorphism and Risk of Cancer: A Meta-Analysis Based on 39 Case-Control Studies

Q Qin, J Lu, H Zhu, L Xu, H Cheng, L Zhan, X Yang… - PloS one, 2014 - journals.plos.org
Background Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear chromatin-associated
enzyme involved in several important cellular processes, particularly in the DNA repair …

Novel mutations of the PARP-1 gene associated with colorectal cancer in the Saudi population

AH Alshammari, MA Shalaby, MS Alanazi… - Asian Pacific Journal …, 2014 - koreascience.kr
Background: colorectal cancer (CRC) is the third most common type of cancers and the
fourth leading cause of death worldwide. In Saudi Arabia, CRC accounts for 8.5% of all …

Contributions of PARP‐1 rs1136410 C>T polymorphism to the development of cancer

H Li, Y Zha, F Du, J Liu, X Li… - Journal of Cellular and …, 2020 - Wiley Online Library
Abstract Poly (ADP‐ribose) polymerase‐1 (PARP‐1) is a nuclear chromatin‐associated
enzyme involved in the DNA damage response. SNP rs1136410 C> T, the most studied …

[HTML][HTML] PARP-1 Val762Ala polymorphism is associated with risk of cervical carcinoma

F Ye, Q Cheng, Y Hu, J Zhang, H Chen - PloS one, 2012 - journals.plos.org
PARP-1 is a nuclear enzyme that plays an important role in DNA repair, recombination,
proliferation and the genome stability. The PARP-1 Val762Ala polymorphism has been …

PARP1 rs1136410 Val762Ala contributes to an increased risk of overall cancer in the East Asian population: a meta-analysis

Y Xin, L Yang, M Su, X Cheng… - Journal of International …, 2021 - journals.sagepub.com
Objectives To investigate the association between poly (ADP-ribose) polymerase 1 (PARP1)
rs1136410 Val762Ala and cancer risk in Asian populations, as published findings remain …

PARP-1 rs3219073 Polymorphism May Contribute to Susceptibility to Lung Cancer

HT Wang, Y Gao, YX Zhao, H Yu, TL Wang… - Genetic Testing and …, 2014 - liebertpub.com
Objective: To investigate the relationship between the PARP-1 rs3219073 C> G
polymorphism and susceptibility to lung cancer in Chinese people. Methods: In accordance …

[HTML][HTML] The C Allele of a synonymous SNP (rs1805414, Ala284Ala) in PARP1 is a risk factor for susceptibility to breast cancer in Saudi patients

M Alanazi, AAK Pathan, JP Shaik… - Asian Pacific Journal …, 2013 - koreascience.kr
Background: Genetic aberrations of DNA repair enzymes are known to be common events
associated with different cancer entities. The aim of the present study was to analyze genetic …

[HTML][HTML] PARP1 gene polymorphisms and the prognosis of esophageal cancer patients from Cixian high-incidence region in Northern China

RM Zhou, Y Li, N Wang, CX Niu, X Huang… - Asian Pacific Journal …, 2020 - ncbi.nlm.nih.gov
Objective: Poly (ADP-ribose) polymerase 1 (PARP1), as a key enzyme in the base excision
repair pathway, plays a crucial role in tumorigenesis and progression. This study aimed to …