Investigating nanoplastics toxicity using advanced stem cell-based intestinal and lung in vitro models
M Busch, H Brouwer, G Aalderink, G Bredeck… - Frontiers in …, 2023 - frontiersin.org
Plastic particles in the nanometer range–called nanoplastics–are environmental
contaminants with growing public health concern. As plastic particles are present in water …
contaminants with growing public health concern. As plastic particles are present in water …
[HTML][HTML] Can the impact of micro-and nanoplastics on human health really be assessed using in vitro models? A review of methodological issues
V Forest, J Pourchez - Environment International, 2023 - Elsevier
Because of the many advantages they offer (strength, low cost, durability, lightweight,
resistance, etc.), plastics are integral part of our daily life with a production constantly rising …
resistance, etc.), plastics are integral part of our daily life with a production constantly rising …
[HTML][HTML] Tiered testing of micro-and nanoplastics using intestinal in vitro models to support hazard assessments
G Bredeck, B Halamoda-Kenzaoui, A Bogni… - Environment …, 2022 - Elsevier
The uncertainty of potential risks associated with micro-and nanoplastics (MNPs) are of
growing public concern. However, the diversity of MNPs in the environment makes a …
growing public concern. However, the diversity of MNPs in the environment makes a …
Application of stem cells in the study of developmental and functional toxicity of endodermal-derived organs caused by nanoparticles
M Julaiti, H Guo, T Cui, N Nijiati, P Huang, B Hu - Toxicology in Vitro, 2024 - Elsevier
Nanoparticles have unique properties that make them useful in biomedicine. However, their
extensive use raises concerns about potential hazards to the body. Therefore, it is crucial to …
extensive use raises concerns about potential hazards to the body. Therefore, it is crucial to …
[HTML][HTML] Development of microfluidic, serum-free bronchial epithelial cells-on-a-chip to facilitate a more realistic in vitro testing of nanoplastics
Most cell culture models are static, but the cellular microenvironment in the body is dynamic.
Here, we established a microfluidic-based in vitro model of human bronchial epithelial cells …
Here, we established a microfluidic-based in vitro model of human bronchial epithelial cells …
Potential human health effects following exposure to nano-and microplastics, lessons learned from nanomaterials
H Brouwer, FLN Van Oijen, H Bouwmeester - Present knowledge in food …, 2023 - Elsevier
A substantial part of the plastic produced worldwide ends up in the environment and
degrades into nano-and microplastics. The particles are ubiquitously present in the air and …
degrades into nano-and microplastics. The particles are ubiquitously present in the air and …
Emergence of nanoplastic in the environment and possible impact on human health
On account of environmental concerns, the fate and adverse effects of plastics have
attracted considerable interest in the past few years. Recent studies have indicated the …
attracted considerable interest in the past few years. Recent studies have indicated the …
In vitro high-throughput toxicological assessment of nanoplastics
Sub-micrometer particles derived from the fragmentation of plastics in the environment can
enter the food chain and reach humans, posing significant health risks. To date, there is a …
enter the food chain and reach humans, posing significant health risks. To date, there is a …
Cytotoxicity Assessment of Nanoplastics and Plasticizers Exposure in In Vitro Lung Cell Culture Systems—A Systematic Review
F Clerigo, S Ferreira, C Ladeira, A Marques-Ramos… - Toxics, 2022 - mdpi.com
Emerging contaminants such as nanoplastics (NPs), as well as manufacturing by-products
such as plasticizers, have gained global attention and concern due to their limited …
such as plasticizers, have gained global attention and concern due to their limited …
Nanoplastics and human health: hazard identification and biointerface
H Lai, X Liu, M Qu - Nanomaterials, 2022 - mdpi.com
Nanoplastics are associated with several risks to the ecology and toxicity to humans.
Nanoplastics are synthetic polymers with dimensions ranging from 1 nm to 1 μm. They are …
Nanoplastics are synthetic polymers with dimensions ranging from 1 nm to 1 μm. They are …