Iron physiology is regulated by a complex interplay of extracellular transport systems,
coordinated transcriptional responses, and iron efflux mechanisms. Dysregulation of iron …

Objective Iron has been implicated in the pathogenesis of brain injury and hydrocephalus
after preterm germinal matrix hemorrhage‐intraventricular hemorrhage, however, it is …

Intracranial haemorrhages, including intracerebral haemorrhage (ICH), intraventricular
haemorrhage (IVH) and subarachnoid haemorrhage (SAH), are leading causes of morbidity …

BACKGROUND: Intracerebral hemorrhage (ICH) is characterized by bleeding into the brain
parenchyma. During an ICH, iron released from the breakdown of hemoglobin creates a …

Intracerebral hemorrhage (ICH) is a leading cause of morbidity and mortality around the
world. Currently, there is no effective medical treatment available to improve functional …

Hemorrhagic stroke, which includes intracere-bral hemorrhage (ICH), intraventricular
hemorrhage (IVH), and subarachnoid hemorrhage (SAH), is associated with significant …

Intracerebral hemorrhage (ICH) is a common subtype of hemorrhagic stroke with
devastating consequences with no specific treatment. There is, however, substantial …

Posthemorrhagic hydrocephalus occurs in up to 30% of infants with high-grade
intraventricular hemorrhage and is associated with the worst neurocognitive outcomes in …

Iron overload plays a key role in brain injury after intracerebral hemorrhage (ICH). We
explored the roles of ferric iron chelator—deferiprone (DFP)—and ferrous iron chelator …

Disturbance of iron homeostasis in the brain plays an important pathogenic role in
aggravating secondary neuronal injury and influencing recovery and functional outcome …