Comparative genomic, transcriptomic and secretomic profiling of Penicillium oxalicum HP7-1 and its cellulase and xylanase hyper-producing mutant EU2106, and …

S Zhao, YS Yan, QP He, L Yang, X Yin, CX Li… - Biotechnology for …, 2016 - Springer
Abstract Background The filamentous fungus Penicillium oxalicum is a potential alternative
to Trichoderma reesei for industrial production of a complete cellulolytic enzyme system for a …

Transcriptomic profiling and genetic analyses reveal novel key regulators of cellulase and xylanase gene expression in Penicillium oxalicum

YS Yan, S Zhao, LS Liao, QP He, YR Xiong… - Biotechnology for …, 2017 - Springer
Background The transition to a more environmentally friendly economy has prompted
studies of modern biorefineries, including the utilization of low-value lignocellulose. The …

Combining manipulation of transcription factors and overexpression of the target genes to enhance lignocellulolytic enzyme production in Penicillium oxalicum

L Gao, Z Li, C Xia, Y Qu, M Liu, P Yang, L Yu… - Biotechnology for …, 2017 - Springer
Background Lignocellulolytic enzymes are the main enzymes to saccharify lignocellulose
from renewable plant biomass in the bio-based economy. The production of these enzymes …

[HTML][HTML] Weighted gene co-expression network analysis identifies critical genes for the production of cellulase and xylanase in Penicillium oxalicum

CX Li, S Zhao, XM Luo, JX Feng - Frontiers in Microbiology, 2020 - frontiersin.org
Genes involved in cellular processes undergo environment-dependent co-regulation, but
the co-expression patterns of fungal cellulase and xylanase-encoding genes remain …

Introduction of heterologous transcription factors and their target genes into Penicillium oxalicum leads to increased lignocellulolytic enzyme production

C Xia, Z Li, Y Xu, P Yang, L Gao, Q Yan, S Li… - Applied microbiology …, 2019 - Springer
Genetic engineering of transcription factors is an efficient strategy to improve lignocellulolytic
enzyme production in fungi. In this study, the xylanase transcriptional regulators of …

Novel Transcription Factor CXRD Regulates Cellulase and Xylanase Biosynthesis in Penicillium oxalicum under Solid-State Fermentation

S Zhao, JX Wang, R Hou, YN Ning… - Applied and …, 2023 - Am Soc Microbiol
Penicillium oxalicum produces an integrated, extracellular cellulase and xylanase system,
strictly regulated by several transcription factors. However, the understanding of the …

Redesigning the regulatory pathway to enhance cellulase production in Penicillium oxalicum

G Yao, Z Li, L Gao, R Wu, Q Kan, G Liu, Y Qu - Biotechnology for biofuels, 2015 - Springer
Background In cellulolytic fungi, induction and repression mechanisms synchronously
regulate the synthesis of cellulolytic enzymes for accurate responses to carbon sources in …

Production of a high-efficiency cellulase complex via β-glucosidase engineering in Penicillium oxalicum

G Yao, R Wu, Q Kan, L Gao, M Liu, P Yang, J Du… - Biotechnology for …, 2016 - Springer
Background Trichoderma reesei is a widely used model cellulolytic fungus, supplying a
highly effective cellulase production system. Recently, the biofuel industry discovered …

The Different Roles of Penicillium oxalicum LaeA in the Production of Extracellular Cellulase and β-xylosidase

Y Li, X Zheng, X Zhang, L Bao, Y Zhu, Y Qu… - Frontiers in …, 2016 - frontiersin.org
Cellulolytic enzyme hydrolysis of lignocellulose biomass to release fermentable sugars is
one of the key steps in biofuel refining. Gene expression of fungal cellulolytic enzymes is …

Insights into high-efficiency lignocellulolytic enzyme production by Penicillium oxalicum GZ-2 induced by a complex substrate

H Liao, S Li, Z Wei, Q Shen, Y Xu - Biotechnology for Biofuels, 2014 - Springer
Background Agricultural residue is more efficient than purified cellulose at inducing
lignocellulolytic enzyme production in Penicillium oxalicum GZ-2, but in Trichoderma reesei …