[HTML][HTML] In vivo lensless microscopy via a phase mask generating diffraction patterns with high-contrast contours

JK Adams, D Yan, J Wu, V Boominathan… - Nature Biomedical …, 2022 - nature.com
The simple and compact optics of lensless microscopes and the associated computational
algorithms allow for large fields of view and the refocusing of the captured images. However …

Lensless imaging and sensing

A Ozcan, E McLeod - Annual review of biomedical engineering, 2016 - annualreviews.org
High-resolution optical microscopy has traditionally relied on high-magnification and high–
numerical aperture objective lenses. In contrast, lensless microscopy can provide high …

Optically sectioned in vivo imaging with speckle illumination HiLo microscopy

D Lim, TN Ford, KK Chu, J Mertz - Journal of biomedical optics, 2011 - spiedigitallibrary.org
We present a simple wide-field imaging technique, called HiLo microscopy, that is capable
of producing optically sectioned images in real time, comparable in quality to confocal laser …

Interferometric synthetic aperture microscopy

TS Ralston, DL Marks, P Scott Carney, SA Boppart - Nature physics, 2007 - nature.com
State-of-the-art methods in high-resolution three-dimensional optical microscopy require that
the focus be scanned through the entire region of interest. However, an analysis of the …

[HTML][HTML] Lensless diffractive imaging with ultra-broadband table-top sources: from infrared to extreme-ultraviolet wavelengths

S Witte, VT Tenner, DWE Noom… - Light: Science & …, 2014 - nature.com
Lensless imaging is an approach to microscopy in which a high-resolution image of an
object is reconstructed from one or more measured diffraction patterns, providing a solution …

Field-portable wide-field microscopy of dense samples using multi-height pixel super-resolution based lensfree imaging

A Greenbaum, U Sikora, A Ozcan - Lab on a Chip, 2012 - pubs.rsc.org
We report a field-portable lensfree microscope that can image dense and connected
specimens with sub-micron resolution over a large field-of-view of∼ 30 mm2 (ie,∼ 6.4 …

Universal autofocus for quantitative volumetric microscopy of whole mouse brains

L Silvestri, MC Müllenbroich, I Costantini… - Nature …, 2021 - nature.com
Unbiased quantitative analysis of macroscopic biological samples demands fast imaging
systems capable of maintaining high resolution across large volumes. Here we introduce …

Adaptive optics via pupil segmentation for high-resolution imaging in biological tissues

N Ji, DE Milkie, E Betzig - Nature methods, 2010 - nature.com
Biological specimens are rife with optical inhomogeneities that seriously degrade imaging
performance under all but the most ideal conditions. Measuring and then correcting for these …

Instantaneous isotropic volumetric imaging of fast biological processes

N Wagner, N Norlin, J Gierten, G De Medeiros… - Nature …, 2019 - nature.com
To capture highly dynamic biological processes at cellular resolution is a recurring
challenge in biology. Here we show that combining selective-volume illumination with …

From micro to nano: recent advances in high-resolution microscopy

Y Garini, BJ Vermolen, IT Young - Current opinion in biotechnology, 2005 - Elsevier
Improving the spatial resolution of optical microscopes is important for a vast number of
applications in the life sciences. Optical microscopy allows intact samples and living cells to …