Introduction Chronic apical periodontitis (CAP) is a common infectious disease of the oral
cavity. Immune responses and osteoclastogenesis of monocytes/macrophages play a …

Chronic apical periodontitis (CAP) is a unique dynamic interaction between microbial
invasions and host defense mechanisms, resulting in infiltration of immune cells, bone …

Background Periodontitis is a major inflammatory disease of the oral mucosa that is not
limited to the oral cavity but also has systemic consequences. Although the importance of …

Periodontitis is a highly prevalent chronic inflammatory disease leading to periodontal tissue
breakdown and subsequent tooth loss, in which excessive host immune response accounts …

Resulting from bacterial infection, apical periodontitis (AP) is a common inflammatory
disease of the periapical region of the tooth. The regeneration of the destroyed periapical …

Background Monocytes are an important cell type in chronic periodontitis (CP) by interacting
with oral bacteria and mediating host immune response. The aim of this study was to reveal …

Abstract Aim Endothelial cells (EDs) play a key role in angiogenesis and are associated with
granulomatous lesions in patients with chronic apical periodontitis (CAP). This study aimed …

Owing to the high prevalence of periodontitis and its impact on quality of life, a rigorous
characterization of periodontal tissue is necessary. However, this has previously been …

Background and objective Periodontitis is a common oral disease closely related to immune
response and this study is aimed to identify the key immune-related pathogenic genes and …

Inflammatory bowel disease (IBD) is a common immune-related disease of the
gastrointestinal tract that affects many people around the world. Extraintestinal …