This review discusses the ways in which anaesthetists can optimize anaesthetic–analgesic
drug administration by utilizing pharmacokinetic and pharmacodynamic information. We …

The drugs used in the clinical practice of anesthesiology, specifically the intravenously
administered compounds that create the hypnotic aspect (unconsciousness) and the …

Pharmacokinetic (PK)/pharmacodynamic (PD) modeling has made an enormous
contribution to intravenous anesthesia. PK/PD models have provided us with insight into the …

Administration and monitoring of intravenous anesthetics : Current Opinion in Anesthesiology
Administration and monitoring of intravenous anesthetics : Current Opinion in Anesthesiology …

Pharmacokinetics explains what happens to a drug in the body, whereas
pharmacodynamics describes the actions produced by the drug on the body. Therefore, the …

Pharmacokinetic–pharmacodynamic modeling in anesthesia, inte... : Current Opinion in
Anesthesiology Pharmacokinetic–pharmacodynamic modeling in anesthesia, intensive care and …

The relationship among drug dosing, drug concentra-tion, and drug response in anesthesia
is complex and differs considerably from the steady-state equilibrium pharmacokinetics that …

This thesis investigates the design and performance of a controller for the maintenance of
anesthesia [ie anaesthesia] during surgery. The controller is designed to be robustly stable …

Automated Drug Delivery in Anesthesia provides a full review of available tools and
methods on the drug delivery of anesthesia, bridging the gap between academic …

Target controlled infusion (TCI) is a clinically-available and widely-used computer-controlled
method of drug administration, adjusting the drug titration towards user selected plasma-or …