Neuropsychiatric lupus: new mechanistic insights and future treatment directions

N Schwartz, AD Stock, C Putterman - Nature Reviews Rheumatology, 2019 - nature.com
Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central
nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS …

[PDF][PDF] Neuropsychiatric systemic lupus erythematosus: a 2021 update on diagnosis, management, and current challenges

S Sarwar, AS Mohamed, S Rogers, ST Sarmast… - Cureus, 2021 - cureus.com
Patients with systemic lupus erythematosus (SLE) experience neuropsychiatric symptoms.
The term neuropsychiatric SLE (NPSLE) is a generic term that refers to a series of …

Advances in the diagnosis, pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus

E Moore, MW Huang, C Putterman - Current opinion in …, 2020 - journals.lww.com
Neuropsychiatric involvement of SLE includes a variety of symptoms that impact quality of
life and patient prognosis. There have been recent advances in improving the diagnosis of …

The management of neuropsychiatric lupus in the 21st century: still so many unmet needs?

M Govoni, JG Hanly - Rheumatology, 2020 - academic.oup.com
Neuropsychiatric (NP) events occur in the majority of patients with SLE and predominantly
affect the CNS in addition to the peripheral and autonomic systems. Approximately 30% of …

Nervous system disease in systemic lupus erythematosus: current status and future directions

JG Hanly, E Kozora, SD Beyea… - Arthritis & …, 2019 - Wiley Online Library
The American College of Rheumatology's case definitions for 19 neuropsychiatric
syndromes in systemic lupus erythematosus (SLE) constitute a comprehensive classification …

Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers

H Jeltsch-David, S Muller - Nature Reviews Neurology, 2014 - nature.com
Systemic lupus erythematosus (SLE) is a complex clinical syndrome, elements of which
remain poorly understood. Although recognized over 140 years ago when Kaposi recorded …

[HTML][HTML] Management of neuropsychiatric systemic lupus erythematosus: current approaches and future perspectives

C Magro-Checa, EJ Zirkzee, TW Huizinga… - Drugs, 2016 - Springer
Neuropsychiatric systemic lupus erythematosus (NPSLE) is a generic definition referring to a
series of neurological and psychiatric symptoms directly related to systemic lupus …

[HTML][HTML] Neuropsychiatric lupus: a mosaic of clinical presentations

S Kivity, N Agmon-Levin, G Zandman-Goddard… - BMC medicine, 2015 - Springer
Neuropsychiatric symptoms affect nearly half of the patients with systemic lupus
erythematosus; however, the effect on disease severity, quality of life, and prognosis is …

[HTML][HTML] The conundrum of neuropsychiatric systemic lupus erythematosus: current and novel approaches to diagnosis

JS Emerson, SM Gruenewald, L Gomes… - Frontiers in …, 2023 - frontiersin.org
Recognising neuropsychiatric involvement by systemic lupus erythematosus (SLE) is of
growing importance, however many barriers to this exist at multiple levels of our currently …

[HTML][HTML] Pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus: A review

Y Liu, Z Tu, X Zhang, K Du, Z Xie, Z Lin - Frontiers in Cell and …, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease with a
complex pathogenesis. Neuropsychiatric systemic lupus erythematosus (NPSLE) is a …