Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Galanin–25 years with a multitalented neuropeptide: Galanin, galanin receptors and drug targets

K Mitsukawa, X Lu, T Bartfai - Cellular and Molecular Life Sciences, 2008 - Springer
Galanin, a neuropeptide widely expressed in the central and peripheral nervous systems
and in the endocrine system, has been shown to regulate numerous physiological and …

The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease

R Lang, AL Gundlach, B Kofler - Pharmacology & therapeutics, 2007 - Elsevier
The galanin peptide family consists of the “parental” galanin, galanin-message-associated
peptide (GMAP) which derives from the same peptide precursor gene product as galanin …

Galanin receptor subtypes and ligand binding

A Florén, T Land, Ü Langel - Neuropeptides, 2000 - Elsevier
Galanin is a neuropeptide initiating its multiple biological effects by binding to different
subtypes of seven transmembrane spanning galanin receptors, thus transducing the …

[HTML][HTML] Galanin receptors and ligands

KEB Webling, J Runesson, T Bartfai… - Frontiers in …, 2012 - frontiersin.org
The neuropeptide galanin was first discovered 30 years ago. Today, the galanin family
consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide …

Galanin: a biologically active peptide

ME Vrontakis - Current Drug Targets-CNS & Neurological …, 2002 - ingentaconnect.com
Galanin is a biologically active neuropeptide, widely distributed in the central and peripheral
nervous systems and the endocrine system. The amino acid sequence of galanin is very …

Galanin and its receptors in neurological disorders

L Lundström, A Elmquist, T Bartfai, Ü Langel - Neuromolecular medicine, 2005 - Springer
Galanin is a highly inducible neuropeptide, showing distinct up-regulation after pathological
disturbance within the nervous system. Significant increase in galanin expression is …

Differential intracellular signaling of the GalR1 and GalR2 galanin receptor subtypes

S Wang, T Hashemi, S Fried, AL Clemmons… - Biochemistry, 1998 - ACS Publications
The diverse physiological functions exerted by the neuropeptide galanin may be regulated
by multiple G protein-coupled receptor subtypes and intracellular signaling pathways. Three …

Galanin receptor subtypes

TA Branchek, KE Smith, C Gerald… - Trends in pharmacological …, 2000 - cell.com
The neuropeptide galanin, which is widely expressed in brain and peripheral tissues, exerts
a broad range of physiological effects. Pharmacological studies using peptide analogues …

Molecular cloning and pharmacological characterization of a new galanin receptor subtype

S Wang, T Hashemi, C He, C Strader, M Bayne - Molecular Pharmacology, 1997 - ASPET
Galanin, a 29–30-amino acid neuropeptide, is widely distributed in central and peripheral
systems and mediates a variety of physiological functions. Pharmacological studies have …