Carcinogenesis, cancer therapy and chemoprevention
MV Blagosklonny - Cell Death & Differentiation, 2005 - nature.com
Carcinogenesis and cancer therapy are two sides of the same coin, such that the same
cytotoxic agent can cause cancer and be used to treat cancer. This review links …
cytotoxic agent can cause cancer and be used to treat cancer. This review links …
[PDF][PDF] Current mechanistic approaches to the chemoprevention of cancer
VE Steele - BMB Reports, 2003 - Citeseer
The prevention of cancer is one of the most important public health and medical practices of
the 21st century. We have made much progress in this new emerging field, but so much …
the 21st century. We have made much progress in this new emerging field, but so much …
Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy
J Zhang, YH Chen, Q Lu - Future oncology, 2010 - Taylor & Francis
Carcinogenesis is the uncontrolled growth of cells gaining the potential to invade and
disrupt vital tissue functions. This malignant process includes the occurrence of …
disrupt vital tissue functions. This malignant process includes the occurrence of …
Molecular regulation of carcinogenesis: friend and foe
An explosion of knowledge on the molecular and cellular mechanisms that mediate
carcinogenesis has occurred in recent years. Although cancer has existed for over a million …
carcinogenesis has occurred in recent years. Although cancer has existed for over a million …
Drug resistance in cancer: an overview
G Housman, S Byler, S Heerboth, K Lapinska… - Cancers, 2014 - mdpi.com
Cancers have the ability to develop resistance to traditional therapies, and the increasing
prevalence of these drug resistant cancers necessitates further research and treatment …
prevalence of these drug resistant cancers necessitates further research and treatment …
Principles of resistance to targeted cancer therapy: lessons from basic and translational cancer biology
AJ Sabnis, TG Bivona - Trends in molecular medicine, 2019 - cell.com
Identification of the genomic drivers of cancer has led to the clinical development of targeted
therapies that strike at the heart of many malignancies. Nonetheless, many cancers outsmart …
therapies that strike at the heart of many malignancies. Nonetheless, many cancers outsmart …
Identifying and targeting the cause of cancer is needed to cure cancer
A Adjiri - Oncology and therapy, 2016 - Springer
Cancer cells continue to challenge scientists and oncologists due to the phenomenon of
resistance. Moreover, recurrence, as seen in many treated patients, shows that currently …
resistance. Moreover, recurrence, as seen in many treated patients, shows that currently …
Chemoprevention: general perspective
I Shureiqi, P Reddy, DE Brenner - Critical reviews in oncology/hematology, 2000 - Elsevier
Chemoprevention is the use of natural or synthetic compounds to block, reverse, or prevent
the development of invasive cancers. Cellular carcinogenesis forms the biologic basis for …
the development of invasive cancers. Cellular carcinogenesis forms the biologic basis for …
Cell signaling and cancer: a mechanistic insight into drug resistance
Drug resistance is a major setback for advanced therapeutics in multiple cancers. The
increasing prevalence of this resistance is a growing concern and bitter headache for the …
increasing prevalence of this resistance is a growing concern and bitter headache for the …
Development of cancer chemopreventive drugs based on mechanistic approaches
VE Steele, GJ Kelloff - Mutation Research/Fundamental and Molecular …, 2005 - Elsevier
One of the most important medical practices of the 21st century is the chemoprevention of
cancer. Much progress has been made in this new emerging field, but much work remains …
cancer. Much progress has been made in this new emerging field, but much work remains …