The association between C-reactive protein, Interleukin-6 and depression among older adults in the community: a systematic review and meta-analysis

KJ Smith, B Au, L Ollis, N Schmitz - Experimental gerontology, 2018 - Elsevier
Previous research indicates there may be an association between inflammation and
depression in older adults but results are inconsistent. Therefore, the aim of this review was …

The longitudinal associations between C‐reactive protein and depressive symptoms: evidence from the English Longitudinal Study of Ageing (ELSA)

B Au, KJ Smith, G Gariépy… - International journal of …, 2015 - Wiley Online Library
Objectives The inflammatory marker C‐reactive protein (CRP) is associated with depression.
We examined the directional relations between CRP and symptoms of depression among …

Inflammatory markers in late-life depression: results from a population-based study

MA Bremmer, ATF Beekman, DJH Deeg… - Journal of affective …, 2008 - Elsevier
BACKGROUND: Previous studies have reported conflicting results concerning the
association between several inflammatory markers and depression. The association …

Inflammatory proteins and depression in the elderly

H Tiemeier, A Hofman, HR van Tuijl, AJ Kiliaan… - …, 2003 - journals.lww.com
Background. Clinical studies suggest that depression may be accompanied by an activation
of the inflammatory response system. We investigated the relation of cytokine interleukin-6 …

The longitudinal associations of inflammatory biomarkers and depression revisited: systematic review, meta-analysis, and meta-regression

N Mac Giollabhui, TH Ng, LM Ellman, LB Alloy - Molecular psychiatry, 2021 - nature.com
The innate immune system is dysregulated in depression; however, less is known about the
longitudinal associations of depression and inflammatory biomarkers. We investigated the …

Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study

BWJH Penninx, SB Kritchevsky, K Yaffe, AB Newman… - Biological …, 2003 - Elsevier
BACKGROUND: Patients with major depression have elevated levels of inflammatory
cytokines. We examined the link between inflammatory markers and depressed mood in a …

Association of inflammation with specific symptoms of depression in a general population of older people: The English Longitudinal Study of Ageing

J White, M Kivimäki, M Jokela, GD Batty - Brain, Behavior, and Immunity, 2017 - Elsevier
Elevated levels of inflammatory markers, such as C-reactive protein, are well documented in
people with depression. Few studies have examined whether the association between …

CRP, IL-6 and depression: a systematic review and meta-analysis of longitudinal studies

V Valkanova, KP Ebmeier, CL Allan - Journal of affective disorders, 2013 - Elsevier
Background Inflammatory markers are raised in cross-sectional studies of depressed
patients and may represent an important mediating factor for behaviour, neural plasticity and …

Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis

MB Howren, DM Lamkin, J Suls - Psychosomatic medicine, 2009 - journals.lww.com
Objective: To assess the magnitude and direction of associations of depression with C-
reactive protein (CRP), interleukin (IL)-1, and IL-6 in community and clinical samples …

[HTML][HTML] IL-1β, IL-6, TNF-α and CRP in elderly patients with depression or Alzheimer's disease: systematic review and meta-analysis

A Ng, WW Tam, MW Zhang, CS Ho, SF Husain… - Scientific reports, 2018 - nature.com
We carried out systematic review and meta-analysis to evaluate whether peripheral levels of
pro-inflammatory markers including Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6), Tumor …