Background Colon cancer (CC) is one of the most common malignancies worldwide.
Characterization of new prognostic biomarkers for right-sided CC (RCC) and left-sided CC …

A new study design based on cross-validation of the age at the onset of rectal cancer and
the differences between the frequency distributions of relevant genes in 2 groups was …

Increasing evidence suggests that HLA‐DRB1 alleles reduce or increase the risk of
developing ulcerative colitis‐associated colorectal carcinoma (CRC) tumors. However, the …

Human leukocyte antigen (HLA)-G has been considered as an immune modulator in several
types of cancers. Its genetic polymorphisms may potentially affect the risk of developing …

Objective Reduced diversity at Human Leukocyte Antigen (HLA) loci may adversely affect
the host's ability to recognize tumor neoantigens and subsequently increase disease …

Background: Colorectal cancer (CRC) is a significant global health challenge with
increasing incidence and mortality rates in developing countries. Genome-wide association …

Background: Evasion of immune surveillance and suppression of the immune system are
important hallmarks of tumour development in colon cancer. The goal of this study was to …

Purpose The association of human leucocyte antigen (HLA) class I expression levels with
the clinical course of many malignancies reflects their crucial role in the recognition and …

Genetic factors play important roles in colorectal carcinogenesis. This study was aimed to
evaluate the effects of gene expression‐related copy number variations (CNVs) on the risk …

Common methods for identifying cancer‑related genes are solely based on differences
between gene frequencies in the disease and control groups, and do not take into account …