Oxidative stress in Parkinson's disease

P Jenner - Annals of Neurology: Official Journal of the …, 2003 - Wiley Online Library
Oxidative stress contributes to the cascade leading to dopamine cell degeneration in
Parkinson's disease (PD). However, oxidative stress is intimately linked to other components …

Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance

C Zhou, Y Huang, S Przedborski - … of the new York Academy of …, 2008 - Wiley Online Library
Parkinson's disease (PD) is a common adult‐onset neurodegenerative disorder. Typically
PD is a sporadic neurological disorder, and over time affected patients see their disability …

Does oxidative stress participate in nerve cell death in Parkinson's disease?

EC Hirsch - European neurology, 1993 - karger.com
Parkinson's disease is characterized by a massive neuronal loss in several cell groups of
the midbrain. However, the most consistent lesions are observed in dopaminergic systems …

Oxidative stress and Parkinson's disease

P Jenner - Handbook of clinical neurology, 2007 - Elsevier
Publisher Summary The formation of reactive oxygen and nitrogen species is a normal
physiological event essential for the functioning of the nervous system in healthy individuals …

The oxidant stress hypothesis in Parkinson's disease: evidence supporting it

S Fahn, G Cohen - Annals of neurology, 1992 - Wiley Online Library
Oxidant stress, due to the formation of hydrogen peroxide and oxygen‐derived free radicals,
can cause cell damage due to chain reactions of membrane lipid peroxidation. Because the …

[HTML][HTML] Oxidative stress and cellular pathologies in Parkinson's disease

L Puspita, SY Chung, J Shim - Molecular brain, 2017 - Springer
Parkinson's disease (PD) is a chronic and progressive neurodegeneration of dopamine
neurons in the substantia nigra. The reason for the death of these neurons is unclear; …

Oxidative stress in Parkinson's disease

AHV Schapira - Neuropathology and applied neurobiology, 1995 - Wiley Online Library
Oxidative damage and mitochondrial dysfunction are now considered to be important events
in the cause of dopaminergic cell death in Parkinson's disease (PD). It is not known whether …

Oxidative stress and Parkinson's disease: conflict of oxidant-antioxidant systems

M Hemmati-Dinarvand, M Valilo… - Neuroscience …, 2019 - Elsevier
Parkinson's disease (PD) is defined as a chronic neurodegenerative disorder which is
diagnosed mostly by its clinical manifestations. Reactive oxygen species (ROS) are …

[HTML][HTML] Oxidative stress factors in Parkinson's disease

J Dorszewska, M Kowalska, M Prendecki… - Neural regeneration …, 2021 - journals.lww.com
Parkinson's disease (PD) is the second most common cause of neurodegeneration. Over the
last two decades, various hypotheses have been proposed to explain the etiology of PD …

The role of oxidative stress in Parkinson's disease

V Dias, E Junn, MM Mouradian - Journal of Parkinson's …, 2013 - content.iospress.com
Oxidative stress plays an important role in the degeneration of dopaminergic neurons in
Parkinson's disease (PD). Disruptions in the physiologic maintenance of the redox potential …