[HTML][HTML] Regulation of nitric oxide production in hypothyroidism

ZM Gluvic, MM Obradovic… - Biomedicine & …, 2020 - Elsevier
Hypothyroidism is a common endocrine disorder that predominantly occurs in females. It is
associated with an increased risk of cardiovascular diseases (CVD), but the molecular …

Nitric oxide as a marker for levo-thyroxine therapy in subclinical hypothyroid patients

M Obradovic, Z Gluvic… - Current Vascular …, 2016 - ingentaconnect.com
Subclinical hypothyroidism (SH) is characterized by a mildly elevated concentration of
thyroid stimulating hormone (TSH) despite free thyroxine (FT4) and triiodothyronine (FT3) …

Vascular and renal function in experimental thyroid disorders

F Vargas, JM Moreno… - European Journal of …, 2006 - academic.oup.com
This review focuses on the effects of thyroid hormones in vascular and renal systems.
Special emphasis is given to the mechanisms by which thyroid hormones affect the …

Nitric oxide synthase activity in hyperthyroid and hypothyroid rats

A Quesada, J Sainz, R Wangensteen… - European Journal of …, 2002 - academic.oup.com
Objective Thyroid disorders are accompanied by important changes in haemodynamic and
cardiac functions and renal sodium handling. Since nitric oxide (NO) plays a crucial role in …

Thyroid hormones, oxidative stress, and inflammation

A Mancini, C Di Segni, S Raimondo… - Mediators of …, 2016 - Wiley Online Library
Inflammation and oxidative stress (OS) are closely related processes, as well exemplified in
obesity and cardiovascular diseases. OS is also related to hormonal derangement in a …

Endothelial dysfunction and subclinical hypothyroidism: a brief review

S La Vignera, R Condorelli, E Vicari… - Journal of …, 2012 - Springer
Subclinical hypothyroidism (SH) is characterized by normal serum free T 4 and free T 3
levels and increased serum TSH levels. The relationship between SH and cardiovascular …

Association of lipid peroxidation with endothelial dysfunction in patients with overt hypothyroidism

B Tejovathi, MM Suchitra, V Suresh… - Experimental and …, 2013 - thieme-connect.com
Hypothyroidism is associated with increased oxidative stress. The mechanism underlying
the endothelial dysfunction in thyroid disease is not yet clear. This study aims to investigate …

Thyroid status and nitric oxide in rat arterial vessels

RM McAllister, I Albarracin, EM Price… - Journal of …, 2005 - joe.bioscientifica.com
Thyroid disease has profound effects on cardiovascular function. Hypo-and hyperthyroidism,
for example, are associated with reduced and increased maximal endothelium-dependent …

Overexpression myocardial inducible nitric oxide synthase exacerbates cardiac dysfunction and beta-adrenergic desensitization in experimental hypothyroidism

Q Shao, HJ Cheng, MF Callahan, DW Kitzman… - International journal of …, 2016 - Elsevier
Background Altered nitric oxide synthase (NOS) has been implicated in the pathophysiology
of heart failure (HF). Recent evidence links hypothyroidism to the pathology of HF. However …

Effect of nitrate and l-arginine therapy on nitric oxide levels in serum, heart, and aorta of fetal hypothyroid rats

A Ghasemi, F Mehrazin, S Zahediasl - Journal of physiology and …, 2013 - Springer
Reduced nitric oxide availability and a heterogeneous pattern of nitric oxide synthase
activity in some tissues have been reported in hypothyroidism. This study aimed at …