Simple Summary E. coli harms over 100 million patients worldwide annually. Its toxin
component is lipopolysaccharide, which has various forms, referred to as smooth or rough …

Despite extensive investigations, an effective treatment for sepsis remains elusive and a
better understanding of the inflammatory response to infection is required to identify …

Despite extensive investigations, an effective treatment for sepsis remains elusive and a
better understanding of the inflammatory response to infection is required to identify …

LPCAT2 is a lipid-modifying enzyme that co-localises in lipid rafts with TLR4 and regulates
macrophage inflammatory response; however, its effect on TLR4 co-receptor–CD14 is …

Lysophosphatidylcholine Acyltransferases (LPCATs) are Lipid modifying enzymes that
significantly regulate changes in the glycerophospholipid components of the macrophage …

Sepsis, an overwhelming inflammatory response to infection, is a major cause of morbidity
and mortality worldwide and has no specific therapy. Phospholipid metabolites, such as …

Sepsis is the overwhelming inflammatory response to infection, especially bacterial infection
and associated bacterial products. It has major healthcare impacts, affecting an estimated 19 …

Lipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative
bacteria. As such, it signals monocytes, macrophages and neutrophils to up-regulate …

Lipopolysaccharide (LPS) is a component of the outer membrane of almost all Gram-
negative bacteria and consists of lipid A, core sugars, and O-antigen. LPS is recognized by …

Lipoteichoic acid (LTA), a key cell wall component of Gram-positive bacteria, seems to
function as an immune activator with characteristics very similar to lipopolysaccharide from …