Lipids are present within the cell nucleus where they engage with factors involved in gene
regulation. Cholesterol associates with chromatin in vivo and stimulates nucleosome …

Lipids are present within the cell nucleus, where they engage with factors involved in gene
regulation. Cholesterol associates with chromatin in vivo and stimulates nucleosome …

Transcriptional control is crucial for normal cellular development and is regulated through a
host of mechanisms. Among other methods, cells control transcription across the genome …

The transcriptional corepressor BASP1 requires N-terminal myristoylation for its activity and
functions through interactions with nuclear lipids. Here we determine the role of BASP1 …

Isolated cases of experimental evidence over the last few decades have shown that, where
specifically tested, both prokaryotes and eukaryotes have specific lipid species bound to …

Structural changes in chromatin regulate gene expression and define phenotypic outcomes.
Molecules that bind to the nucleosome, the complex of DNA and histones proteins, are key …

Abstract Changes in chromatin structure regulate gene expression and genome
maintenance. Molecules that bind to the nucleosome, the complex of DNA and histone …

Isolated cases of experimental evidence over the last few decades have shown that, where
specifically tested, both prokaryotes and eukaryotes have specific lipid molecules bound to …

Structural changes in chromatin regulate gene expression and define phenotypic outcomes.
Molecules that bind to the nucleosome, the complex of DNA and histone proteins, are key …

Cholesterol is essential for membrane biogenesis, cell proliferation, and differentiation. The
role of cholesterol in cancer development and the regulation of cholesterol synthesis are still …