The dramatic increase in the prevalence and clinical impact of infections caused by bacteria
producing carbapenemases is a global health concern. Carbapenemase production is …

The rapid spread of multidrug-resistant Gram-negative organisms constitutes one of the
greatest challenges to global health. While Gram-negative organisms have developed …

Carbapenemases are β-lactamases belonging to different Ambler classes (A, B, D) and can
be encoded by both chromosomal and plasmid-mediated genes. These enzymes represent …

Carbapenemases, with versatile hydrolytic capacity against β-lactams, are now an important
cause of resistance of Gram-negative bacteria. The genes encoding for the acquired …

Carbapenemase-producing bacteria have now spread all over the world. Infections caused
by those bacteria are difficult to treat. Therefore, there is an urgent need for accurate and fast …

Carbapenem-resistant Enterobacteriaceae (CRE) have spread rapidly around the world in
the past few years, posing great challenges to human health. The plasmid-mediated …

The emergence and rapid spread of carbapenemases in Enterobacteriaceae,
Pseudomonas and Acinetobacter (EPA) species is becoming a major public health crisis …

Acquired carbapenemases are emerging resistance determinants in Gram-negative
pathogens, including Enterobacteriaceae, Pseudomonas aeruginosa and other Gram …

Infections caused by carbapenemase-producing bacteria are becoming a major clinical and
public health concern. Detection of carbapenemase producing strains is often challenging …

Acquired carbapenemases of the Ambler Classes A, B and D have gradually disseminated
over the past decade among isolates of the Enterobacteriaceae family. Located on highly …