Inflammatory mediators of cerebral endothelium: a role in ischemic brain inflammation
D Stanimirovic, K Satoh - Brain pathology, 2000 - Wiley Online Library
Brain inflammation has been implicated in the development of brain edema and secondary
brain damage in ischemia and trauma. Adhesion molecules, cytokines and leukocyte …
brain damage in ischemia and trauma. Adhesion molecules, cytokines and leukocyte …
Endothelial dysfunction and inflammation in ischemic stroke pathogenesis
A Tuttolomondo, M Daidone… - Current Pharmaceutical …, 2020 - ingentaconnect.com
Stroke is a heterogeneous disease, and within the broad category of brain ischemia and its
subtypes vary dramatically in its etiology. The endothelium can regulate the vascular …
subtypes vary dramatically in its etiology. The endothelium can regulate the vascular …
Alterations in cerebral endothelial cell function in ischemia.
AL Betz - Advances in neurology, 1996 - europepmc.org
As summarized in Fig. 2, nearly all aspects of brain microvascular endothelial cell function
may be affected by ischemia. These alterations not only interfere with BBB functions which …
may be affected by ischemia. These alterations not only interfere with BBB functions which …
Inflammation in stroke and focal cerebral ischemia
J Huang, UM Upadhyay, RJ Tamargo - Surgical neurology, 2006 - Elsevier
BACKGROUND: A growing number of recent investigations have established a critical role
for leukocytes in propagating tissue damage after ischemia and reperfusion in stroke …
for leukocytes in propagating tissue damage after ischemia and reperfusion in stroke …
The induction of ICAM-1 in human cerebromicrovascular endothelial cells (HCEC) by ischemia-like conditions promotes enhanced neutrophil/HCEC adhesion
D Stanimirovic, A Shapiro, J Wong, J Hutchison… - Journal of …, 1997 - Elsevier
Ischemic brain injury is exacerbated by leukocyte infiltration and formation of vasogenic
edema. In this study we demonstrate that intercellular adhesion molecule-1 (ICAM-1) is …
edema. In this study we demonstrate that intercellular adhesion molecule-1 (ICAM-1) is …
Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke
PJ Lindsberg, O Carpe´ n, A Paetau… - Circulation, 1996 - Am Heart Assoc
Background After focal brain ischemia, leukocytes adhere to the perturbed endothelium and
are believed to aggravate reperfusion injury. Although ischemia-induced upregulation of …
are believed to aggravate reperfusion injury. Although ischemia-induced upregulation of …
Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia
G Del Zoppo, I Ginis, JM Hallenbeck… - Brain …, 2000 - Wiley Online Library
Ischemic stroke is a leading cause of death and disability in developed countries. Yet, in
spite of substantial research and development efforts, no specific therapy for stroke is …
spite of substantial research and development efforts, no specific therapy for stroke is …
Temporal modulation of cytokine expression following focal cerebral ischemia in mice
JK Hill, L Gunion-Rinker, D Kulhanek, N Lessov, S Kim… - Brain research, 1999 - Elsevier
There is increasing evidence that the inflammatory response plays an important role in CNS
ischemia. The murine model of focal ischemia, however, remains incompletely …
ischemia. The murine model of focal ischemia, however, remains incompletely …
Inflammatory mechanisms after ischemia and stroke
GH Danton, WD Dietrich - Journal of Neuropathology & …, 2003 - academic.oup.com
Inflammation has been implicated as a secondary injury mechanism following ischemia and
stroke. A variety of experimental models, including thromboembolic stroke, focal and global …
stroke. A variety of experimental models, including thromboembolic stroke, focal and global …
Cytokines and cell adhesion molecules in cerebral ischemia: experimental bases and therapeutic perspectives
L Pantoni, C Sarti, D Inzitari - Arteriosclerosis, thrombosis, and …, 1998 - Am Heart Assoc
The possibility of reopening an occluded cerebral artery by means of thrombolysis has
renewed interest in a number of the several mechanisms that are active during acute …
renewed interest in a number of the several mechanisms that are active during acute …