[HTML][HTML] Oncological outcomes of local excision versus radical surgery for early rectal cancer in the context of staging and surveillance: A systematic review and meta …

MG Fadel, M Ahmed, A Shaw, M Fehervari… - Cancer Treatment …, 2024 - Elsevier
Background Local resection (LR) methods for rectal cancer are generally considered in the
palliative setting or for patients deemed a high anaesthetic risk. This systematic review and …

For patients with early rectal cancer, does local excision have an impact on recurrence, survival, and quality of life relative to radical resection?

AL Halverson, AM Morris, RK Cleary… - Annals of surgical …, 2019 - Springer
Background The most appropriate treatment for early-stage rectal cancers is controversial.
The advantages of local excision regarding morbidity and function must be weighed against …

Local resection versus radical resection for early-stage rectal cancer: a systematic review and meta-analysis

S Tan, C Xu, H Ma, S Chen, Y Yang, Y Zhan… - International Journal of …, 2022 - Springer
Purpose The optimal surgical approach for early-stage rectal cancer remains controversial.
Radical resection is considered to be the gold standard for rectal cancer treatment. More …

Outcomes following completion and salvage surgery for early rectal cancer: a systematic review

HJS Jones, C Cunningham, GA Nicholson… - European Journal of …, 2018 - Elsevier
Objectives To establish outcomes after completion and salvage surgery following local
excision in literature published since 2005, to inform decision-making when offering local …

[HTML][HTML] Long-term oncological outcomes after local excision of T1 rectal cancer

JWA Leijtens, LJH Smits, TWA Koedam… - Techniques in …, 2023 - Springer
Background A growing proportion of patients with early rectal cancer is treated by local
excision only. The aim of this study was to evaluate long-term oncological outcomes and the …

Primary local excision of stage 1 rectal cancer is not associated with worse oncological outcomes when compared with major resection

R Cohen, C Platell - International Journal of Colorectal Disease, 2020 - Springer
Purpose Primary local excision (PLE) for early rectal cancers is associated with decreased
surgical morbidity and mortality compared with major resection (MR). However, it is thought …

[HTML][HTML] Endoscopic and trans-anal local excision vs. radical resection in the treatment of early rectal cancer: A systematic review and network meta-analysis

C Kwik, T El-Khoury, N Pathma-Nathan… - International Journal of …, 2023 - Springer
Purpose The management of early-stage rectal cancer in clinical practice is controversial.
The aim of this network meta-analysis was to compare oncological and postoperative …

The impact of a dedicated multidisciplinary team on the management of early rectal cancer

PG Vaughan‐Shaw, JMD Wheeler… - Colorectal …, 2015 - Wiley Online Library
Aim Local excision of early rectal cancer (ERC a) offers comparable survival and reduced
operative morbidity compared with radical surgery, yet it risks an adverse oncological …

Early-rectal cancer treatment: a decision-tree making based on systematic review and meta-analysis

I Aguirre-Allende, JM Enriquez-Navascues… - Cirugía Española, 2021 - Elsevier
Local excision (LE) has arisen as an alternative to total mesorectal excision for the treatment
of early rectal cancer. Despite a decreased morbidity, there are still concerns about LE …

A systematic review of local excision combined with chemoradiotherapy for early rectal cancer

L Ung, TC Chua, AF Engel - Colorectal Disease, 2014 - Wiley Online Library
Aim Local excision of early rectal cancer is a less morbid alternative to major abdominal
surgery. This review evaluates the role of local excision with neoadjuvant or adjuvant …