Metabolic surgery to treat type 2 diabetes: clinical outcomes and mechanisms of action

F Rubino, PR Schauer, LM Kaplan… - Annual review of …, 2010 - annualreviews.org
Several gastrointestinal (GI) operations that were designed to promote weight loss can
powerfully ameliorate type 2 diabetes mellitus (T2DM). Although T2DM is traditionally …

The role of bariatric surgery to treat diabetes: current challenges and perspectives

C Koliaki, S Liatis, CW Le Roux, A Kokkinos - BMC endocrine disorders, 2017 - Springer
Bariatric surgery is emerging as a powerful weapon against severe obesity and type 2
diabetes mellitus (T2DM). Given its role in metabolic regulation, the gastrointestinal tract …

Metabolic surgery in the treatment algorithm for type 2 diabetes: a joint statement by international diabetes organizations

F Rubino, DM Nathan, RH Eckel, PR Schauer… - Diabetes …, 2016 - Am Diabetes Assoc
BACKGROUND Despite growing evidence that bariatric/metabolic surgery powerfully
improves type 2 diabetes (T2D), existing diabetes treatment algorithms do not include …

Metabolic surgery: the role of the gastrointestinal tract in diabetes mellitus

F Rubino, SL R'bibo, F Del Genio… - Nature reviews …, 2010 - nature.com
Several conventional methods of bariatric surgery can induce long-term remission of type 2
diabetes mellitus (T2DM); novel gastrointestinal surgical procedures are reported to have …

Metabolic surgery for the treatment of type 2 diabetes: A network meta‐analysis of randomized controlled trials

B Cresci, C Cosentino, M Monami… - Diabetes, Obesity and …, 2020 - Wiley Online Library
Aim To compare different types of metabolic surgery (MS) with medical therapy (MT) for the
treatment of type 2 diabetes (T2D). Materials and methods We conducted a network‐meta …

Obesity and diabetes: the impact of bariatric surgery on type-2 diabetes

JB Dixon - World journal of surgery, 2009 - Springer
Weight gain and obesity are driving the global epidemic of type-2 diabetes through
metabolic and inflammatory pathways that cause insulin resistance and impair pancreatic β …

Glucose metabolism after bariatric surgery: implications for T2DM remission and hypoglycaemia

DA Sandoval, ME Patti - Nature Reviews Endocrinology, 2023 - nature.com
Although promising therapeutics are in the pipeline, bariatric surgery (also known as
metabolic surgery) remains our most effective strategy for the treatment of obesity and type 2 …

Bariatric surgery and type 2 diabetes: are there weight loss‐independent therapeutic effects of upper gastrointestinal bypass?

M Chondronikola, LLS Harris… - Journal of internal …, 2016 - Wiley Online Library
Abstract Type 2 diabetes (T2D) is a major worldwide public health concern. Despite a large
armamentarium of T2D medications, a large proportion of patients fail to achieve …

[HTML][HTML] Diabetes remission after bariatric surgery

M Chumakova-Orin, C Vanetta, DP Moris… - World journal of …, 2021 - ncbi.nlm.nih.gov
Over the last decade, obesity rates have continued to rise in the United States as well as
worldwide and are showing no signs of slowing down. This rise is in parallel with the …

Effects of bariatric surgery on glucose homeostasis and type 2 diabetes

D Bradley, F Magkos, S Klein - Gastroenterology, 2012 - Elsevier
Obesity is an important risk factor for type 2 diabetes mellitus (T2DM). Weight loss improves
the major factors involved in the pathogenesis of T2DM, namely insulin action and beta cell …