Ginsenoside Rg1 inhibits apoptosis by increasing autophagy via the AMPK/mTOR signaling in serum deprivation macrophages
P Yang, L Ling, W Sun, J Yang, L Zhang… - Acta biochimica et …, 2018 - academic.oup.com
Abstract Ginsenoside Rg1 (Rg1) has been widely used in a broad range of cardiovascular
and cerebral–vascular diseases because of its unique therapeutic properties. However, the …
and cerebral–vascular diseases because of its unique therapeutic properties. However, the …
20 (S)-Ginsenoside Rg3 promotes HeLa cell apoptosis by regulating autophagy
S Bian, Y Zhao, F Li, S Lu, S Wang, X Bai, M Liu… - Molecules, 2019 - mdpi.com
20 (S)-Ginsenoside Rg3 (GRg3) has various bioactivities including anti-cancer effects and
inhibition of autophagy. However, no reports have investigated the appearance of …
inhibition of autophagy. However, no reports have investigated the appearance of …
Inhibitory effects of ginsenoside Rb1 on early atherosclerosis in ApoE-/-mice via inhibition of apoptosis and enhancing autophagy
P Zhou, W Xie, Y Luo, S Lu, Z Dai, R Wang, X Zhang… - Molecules, 2018 - mdpi.com
Inflammation is a major contributing factor to the progression of atherosclerosis.
Ginsenoside Rb1 (Rb1), an active saponin of Panax notoginseng, has been found to exert …
Ginsenoside Rb1 (Rb1), an active saponin of Panax notoginseng, has been found to exert …
Ginsenoside Rg3 attenuates sepsis-induced injury and mitochondrial dysfunction in liver via AMPK-mediated autophagy flux
W Xing, L Yang, Y Peng, Q Wang, M Gao… - Bioscience …, 2017 - portlandpress.com
Sepsis-led mitochondrial dysfunction has become a critical pathophysiological procedure in
sepsis. Since ginsenosides have been applied in the treatment of mitochondrial dysfunction …
sepsis. Since ginsenosides have been applied in the treatment of mitochondrial dysfunction …
Ginsenoside Rb1 inhibits cardiomyocyte autophagy via PI3K/Akt/mTOR signaling pathway and reduces myocardial ischemia/reperfusion injury
GW Qin, P Lu, L Peng, W Jiang - The American Journal of Chinese …, 2021 - World Scientific
Myocardial ischemia/reperfusion injury (MIRI) is the major cause of myocardial cell damage
in acute myocardial infarction, and its treatment remains a clinical challenge. Ginsenoside …
in acute myocardial infarction, and its treatment remains a clinical challenge. Ginsenoside …
Ginsenoside Rg1 Alleviates Rat Liver Ischemia-Reperfusion Ischemia Through Mitochondrial Autophagy Pathway.
J Lin, Z Qing, H Huang, S Yang… - Alternative Therapies in …, 2023 - search.ebscohost.com
Aim• The aim of this study was to elucidate the potential mechanism of Rg1 in alleviating
hepatic ischemiareperfusion (HIRI) through the mitophagy pathway. Methods• The HIRI rat …
hepatic ischemiareperfusion (HIRI) through the mitophagy pathway. Methods• The HIRI rat …
Ginsenoside Rg1 inhibits autophagy in H9c2 cardiomyocytes exposed to hypoxia/reoxygenation
ZL Zhang, Y Fan, ML Liu - Molecular and cellular biochemistry, 2012 - Springer
Ginsenoside Rg1 promotes antioxidative protection and intracellular calcium homeostasis in
cardiomyocytes hypoxia/reoxygenation (H/R) model. However, the pharmacological effects …
cardiomyocytes hypoxia/reoxygenation (H/R) model. However, the pharmacological effects …
Ginsenoside Rb1 ameliorates autophagy of hypoxia cardiomyocytes from neonatal rats via AMP-activated protein kinase pathway
S Dai, A Hou, S Zhao, X Chen, H Huang… - Chinese journal of …, 2019 - Springer
Objective To investigate whether ginsenoside-Rb1 (Gs-Rb1) improves the CoCl-induced
autophagy of cardiomyocytes via upregulation of adenosine 5′-monophosphate-activated …
autophagy of cardiomyocytes via upregulation of adenosine 5′-monophosphate-activated …
Ginsenoside Rg1 regulates autophagy and endoplasmic reticulum stress via the AMPK/mTOR and PERK/ATF4/CHOP pathways to alleviate alcohol‑induced …
G Tian, J Li, L Zhou - International Journal of Molecular …, 2023 - spandidos-publications.com
It has been reported that ginsenoside Rg1 (G‑Rg1) can alleviate alcoholic liver injury,
cardiac hypertrophy and myocardial ischemia, as well as reperfusion injury. Therefore, the …
cardiac hypertrophy and myocardial ischemia, as well as reperfusion injury. Therefore, the …
Ginsenoside Rb1 attenuates oxygen-glucose deprivation-induced apoptosis in SH-SY5Y cells via protection of mitochondria and inhibition of AIF and cytochrome c …
J Liang, Y Yu, B Wang, B Lu, J Zhang, H Zhang, P Ge - Molecules, 2013 - mdpi.com
To investigate the role of mitochondria in the protective effects of ginsenoside Rb1 on
cellular apoptosis caused by oxygen-glucose deprivation, in this study, MTT assay, TUNEL …
cellular apoptosis caused by oxygen-glucose deprivation, in this study, MTT assay, TUNEL …
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