The SLC39 family of zinc transporters
J Jeong, DJ Eide - Molecular aspects of medicine, 2013 - Elsevier
Zinc is a trace element nutrient that is essential for life. This mineral serves as a cofactor for
enzymes that are involved in critical biochemical processes and it plays many structural …
enzymes that are involved in critical biochemical processes and it plays many structural …
The SLC30 family of zinc transporters–a review of current understanding of their biological and pathophysiological roles
L Huang, S Tepaamorndech - Molecular aspects of medicine, 2013 - Elsevier
Two families of zinc (Zn2+) transporters are involved in zinc homeostasis in the body, SLC30
(ZnT, zinc transporter) and SLC39 (ZIP, Zinc (Zn2+)–Iron (Fe2+) Permease). The two zinc …
(ZnT, zinc transporter) and SLC39 (ZIP, Zinc (Zn2+)–Iron (Fe2+) Permease). The two zinc …
[HTML][HTML] Recent advances in the role of SLC39A/ZIP zinc transporters in vivo
Zinc (Zn), which is an essential trace element, is involved in numerous mammalian
physiological events; therefore, either a deficiency or excess of Zn impairs cellular …
physiological events; therefore, either a deficiency or excess of Zn impairs cellular …
[HTML][HTML] Zinc transporters as potential therapeutic targets: An updated review
Zinc is an essential trace element that plays important roles in the regulation of various
physiological responses in the body. Zinc deficiency is known to cause various health …
physiological responses in the body. Zinc deficiency is known to cause various health …
[HTML][HTML] ZnT5 variant B is a bidirectional zinc transporter and mediates zinc uptake in human intestinal Caco-2 cells
RA Valentine, KA Jackson, GR Christie… - Journal of biological …, 2007 - ASBMB
Zinc is an essential micronutrient, so it is important to elucidate the molecular mechanisms of
zinc homeostasis, including the functional properties of zinc transporters. Mammalian zinc …
zinc homeostasis, including the functional properties of zinc transporters. Mammalian zinc …
The families of zinc (SLC30 and SLC39) and copper (SLC31) transporters
M Schweigel-Röntgen - Current topics in membranes, 2014 - Elsevier
The solute carriers families 30 (SLC30; ZnT), 39 (SLC39; ZIP), and 31 (SLC31; CTR) are
involved in the essential maintenance of cellular zinc (Zn 2+) and copper (Cu 2+) …
involved in the essential maintenance of cellular zinc (Zn 2+) and copper (Cu 2+) …
Efflux and compartmentalization of zinc by members of the SLC30 family of solute carriers
RD Palmiter, L Huang - Pflügers Archiv, 2004 - Springer
All of the members of this family are thought to facilitate zinc efflux from the cytoplasm either
into various intracellular compartments (endosomes, secretory granules, synaptic vesicles …
into various intracellular compartments (endosomes, secretory granules, synaptic vesicles …
Zinc transporter proteins
AK Baltaci, K Yuce - Neurochemical research, 2018 - Springer
Zinc, which is involved in the structure of all enzyme classes, is a micro nutrient element and
necessary for growth and development. The ability of zinc to function without causing toxic …
necessary for growth and development. The ability of zinc to function without causing toxic …
[HTML][HTML] The emerging role of zinc transporters in cellular homeostasis and cancer
E Bafaro, Y Liu, Y Xu, RE Dempski - Signal transduction and targeted …, 2017 - nature.com
Zinc is an essential micronutrient that plays a role in the structural or enzymatic functions of
many cellular proteins. Cellular zinc homeostasis involves the opposing action of two …
many cellular proteins. Cellular zinc homeostasis involves the opposing action of two …
An overview of a wide range of functions of ZnT and Zip zinc transporters in the secretory pathway
T Kambe - Bioscience, biotechnology, and biochemistry, 2011 - Taylor & Francis
Zinc plays essential roles in the early secretory pathway for a number of secretory,
membrane-bound, and endosome/lysosome-resident enzymes. It enables the enzymes to …
membrane-bound, and endosome/lysosome-resident enzymes. It enables the enzymes to …