New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways

B Atto, MS Eapen, P Sharma, U Frey, AJ Ammit… - Clinical …, 2019 - portlandpress.com
Chronic respiratory diseases are among the leading causes of mortality worldwide, with the
major contributor, chronic obstructive pulmonary disease (COPD) accounting for …

[HTML][HTML] Unmet needs in the management of exacerbations of chronic obstructive pulmonary disease

K Waeijen-Smit, S Houben-Wilke… - Internal and Emergency …, 2021 - Springer
Exacerbations of chronic obstructive pulmonary disease (COPD) are episodes of acute
worsening of respiratory symptoms that require additional therapy. These events play a …

Pathogenesis of bacterial exacerbations of COPD

SB Veeramachaneni, S Sethi - COPD: Journal of Chronic …, 2006 - Taylor & Francis
Acute exacerbations are significant events in the course of COPD. The pathogenesis of
exacerbations was poorly understood, specifically, the role of bacteria was highly …

[HTML][HTML] Exacerbation of chronic obstructive pulmonary disease

X Zhou, Q Li, X Zhou - Cell biochemistry and biophysics, 2015 - Springer
Chronic obstructive pulmonary disease (COPD) is a disease with high prevalence and
substantial associated economical burden. A significant determinant of quality of life, long …

Lung microbiology and exacerbations in COPD

V Beasley, PV Joshi, A Singanayagam… - … journal of chronic …, 2012 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is the most common chronic respiratory
condition in adults and is characterized by progressive airflow limitation that is not fully …

[HTML][HTML] Resolving viral-induced secondary bacterial infection in COPD: a concise review

H Wang, D Anthony, S Selemidis, R Vlahos… - Frontiers in …, 2018 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a leading cause of disability and death
world-wide, where chronic inflammation accelerates lung function decline. Pathological …

Mechanisms of chronic obstructive pulmonary disease exacerbations

JA Wedzicha - Annals of the American Thoracic Society, 2015 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) exacerbations are important events that
contribute to worsening health status, disease progression, and mortality. They are mainly …

Acute Exacerbation and Respiratory InfectionS in COPD (AERIS): protocol for a prospective, observational cohort study

S Bourne, C Cohet, V Kim, A Barton, A Tuck, E Aris… - BMJ open, 2014 - bmjopen.bmj.com
Introduction The aetiology of acute exacerbations of chronic obstructive pulmonary disease
(COPD) remains incompletely understood and strategies for treatment and prevention have …

[HTML][HTML] Role of antimicrobial agents in the management of exacerbations of COPD

S Sharma, N Anthonisen - Treatments in respiratory medicine, 2005 - Springer
Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are a common
occurrence and characterize the natural history of the disease. Over the past decade, new …

The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPD

JM Leung, PY Tiew, M Mac Aogáin, KF Budden… - …, 2017 - Wiley Online Library
ABSTRACT COPD is a major global concern, increasingly so in the context of ageing
populations. The role of infections in disease pathogenesis and progression is known to be …