Measuring electrical activity of neural networks by microelectrode array (MEA) has recently
shown promise for screening level assessments of chemical toxicity on network …

Because the Developmental Neurotoxicity Testing Guidelines require large numbers of
animals and is expensive, development of in vitro approaches to screen chemicals for …

There is a need for methods to screen and prioritize chemicals for potential hazard,
including neurotoxicity. Microelectrode array (MEA) systems enable simultaneous …

Neurotoxicity can be defined by the ability of a drug or chemical to alter the physiology,
biochemistry, or structure of the nervous system in a manner that may negatively impact the …

Microelectrode array (MEA) recordings are increasingly being used as an in vitro method to
detect and characterize the ability of drugs, chemicals and particles to cause neurotoxicity …

Neurotoxicity testing of chemicals, drug candidates, and environmental pollutants still relies
on extensive in vivo studies that are very costly, time‐consuming, and ethically debated due …

Neuronal assemblies within the nervous system produce electrical activity that can be
recorded in terms of action potential patterns. Such patterns provide a sensitive endpoint to …

Neuronal networks cultured on microelectrode array (MEA) neurochips provide a testing
platform for neuroactive compounds such as neurotoxicants and neuropharmaceuticals …

Microelectrode arrays (MEAs) have been in use over the past decade and a half to study
multiple aspects of electrically excitable cells. In particular, MEAs have been applied to …

Microelectrode arrays (MEAs) can be used to detect drug and chemical induced changes in
neuronal network function and have been used for neurotoxicity screening. As a proof-of …