Long-term excessive dietary phosphate intake increases arterial blood pressure, activates the renin–angiotensin–aldosterone system, and stimulates sympathetic …
N Latic, M Peitzsch, A Zupcic, J Pietzsch, RG Erben - Biomedicines, 2022 - mdpi.com
Increased dietary phosphate intake has been associated with severity of coronary artery
disease, increased carotid intima–media thickness, left ventricular hypertrophy (LVH), and …
disease, increased carotid intima–media thickness, left ventricular hypertrophy (LVH), and …
High phosphate diet increases arterial blood pressure via a parathyroid hormone mediated increase of renin
M Bozic, S Panizo, MA Sevilla, M Riera… - Journal of …, 2014 - journals.lww.com
Background: There is growing evidence suggesting that phosphate intake is associated with
blood pressure levels. However, data from epidemiological studies show inconsistent …
blood pressure levels. However, data from epidemiological studies show inconsistent …
Hyperphosphatemia and cardiovascular disease
C Zhou, Z Shi, N Ouyang, X Ruan - Frontiers in Cell and …, 2021 - frontiersin.org
Hyperphosphatemia or even serum phosphate levels within the “normal laboratory range”
are highly associated with increased cardiovascular disease risk and mortality in the general …
are highly associated with increased cardiovascular disease risk and mortality in the general …
Effects of dietary phosphate on glucose and lipid metabolism
M Abuduli, H Ohminami, T Otani… - American Journal …, 2016 - journals.physiology.org
Recent epidemiological and animal studies have suggested that excess intake of phosphate
(Pi) is a risk factor for the progression of chronic kidney disease and its cardiovascular …
(Pi) is a risk factor for the progression of chronic kidney disease and its cardiovascular …
A chronic high phosphate intake in mice is detrimental for bone health without major renal alterations
M Ugrica, C Bettoni, S Bourgeois… - Nephrology Dialysis …, 2021 - academic.oup.com
Background Phosphate intake has increased in the last decades due to a higher
consumption of processed foods. This higher intake is detrimental for patients with chronic …
consumption of processed foods. This higher intake is detrimental for patients with chronic …
Chronic High Phosphate Intake in Mice Affects Macronutrient Utilization and Body Composition
M Ugrica, N Gehring, P Giesbertz… - Molecular Nutrition & …, 2022 - Wiley Online Library
Scope In the last decades, dietary phosphate intake has increased due to a higher
consumption of ultraprocessed food. This higher intake has an impact on body composition …
consumption of ultraprocessed food. This higher intake has an impact on body composition …
High phosphate‐induced progressive proximal tubular injury is associated with the activation of Stat3/Kim‐1 signaling pathway and macrophage recruitment
B Richter, T Kapanadze, N Weingärtner… - The FASEB …, 2022 - Wiley Online Library
Dietary phosphate intake in the Western population greatly exceeds the recommended
dietary allowance and is linked to enhanced cardiovascular and all‐cause mortality. It is …
dietary allowance and is linked to enhanced cardiovascular and all‐cause mortality. It is …
High phosphate impairs arterial endothelial function through AMPK‐related pathways in mouse resistance arteries
W Hu, S Jiang, Y Liao, J Li, F Dong, J Guo… - Acta …, 2021 - Wiley Online Library
Aims In patients with renal disease, high serum phosphate shows a relationship with
cardiovascular risk. We speculate that high phosphate (HP) impairs arterial vasodilation via …
cardiovascular risk. We speculate that high phosphate (HP) impairs arterial vasodilation via …
High dietary phosphate intake induces hypertension and augments exercise pressor reflex function in rats
M Mizuno, JH Mitchell, S Crawford… - American Journal …, 2016 - journals.physiology.org
An increasing number of studies have linked high dietary phosphate (Pi) intake to
hypertension. It is well established that the rise in sympathetic nerve activity (SNA) and …
hypertension. It is well established that the rise in sympathetic nerve activity (SNA) and …
A high phosphate diet lowers blood pressure in spontaneously hypertensive rats.
RJ Bindels, LA Van Den Broek, SJ Hillebrand… - …, 1987 - Am Heart Assoc
Plasma phosphate values are significantly lower in spontaneously hypertensive rats (SHR)
than in normotensive Wistar-Kyoto rats (WKY). In this study, we increased plasma phosphate …
than in normotensive Wistar-Kyoto rats (WKY). In this study, we increased plasma phosphate …
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