Recent advances in intranasal liposomes for drug, gene, and vaccine delivery

VA Duong, TTL Nguyen, HJ Maeng - Pharmaceutics, 2023 - mdpi.com
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …

Liposomes as delivery systems for nasal vaccination: strategies and outcomes

B Heurtault, B Frisch, F Pons - Expert opinion on drug delivery, 2010 - Taylor & Francis
Importance of the field: Among the particulate systems that have been envisaged in vaccine
delivery, liposomes are very attractive. These phospholipid vesicles can indeed deliver a …

Liposomal formulations for nose-to-brain delivery: recent advances and future perspectives

SS Hong, KT Oh, HG Choi, SJ Lim - Pharmaceutics, 2019 - mdpi.com
Restricted drug entry to the brain that is closely associated with the existence of the blood
brain barrier (BBB) has limited the accessibility of most potential active therapeutic …

Nose-to-brain/spinal cord delivery kinetics of liposomes with different surface properties

T Kurano, T Kanazawa, A Ooba, Y Masuyama… - Journal of Controlled …, 2022 - Elsevier
The administration of liposomes via nose-to-brain delivery is expected to become a strategy
for efficient drug delivery to the central nervous system. Efficient nose-to-brain delivery and …

Topical and mucosal liposomes for vaccine delivery

E Lilia Romero, MJ Morilla - Wiley Interdisciplinary Reviews …, 2011 - Wiley Online Library
Mucosal (and in minor extent transcutanous) stimulation can induce local or distant mucosa
secretory IgA. Liposomes and other vesicles as mucosal and transcutaneous adjuvants are …

Brain delivery of proteins by the intranasal route of administration: a comparison of cationic liposomes versus aqueous solution formulations

MM Migliore, TK Vyas, RB Campbell, MM Amiji… - Journal of …, 2010 - Elsevier
The goal of this research was to evaluate the effectiveness of cationic liposomes for
intranasal administration of proteins to the brain. Cationic liposomes were loaded with a …

Pharmaceutical aspects of intranasal delivery of vaccines using particulate systems

S Sharma, TKS Mukkur, HAE Benson… - Journal of pharmaceutical …, 2009 - Elsevier
The nasal route offers a promising opportunity for the delivery of vaccines. This review
analyses the opportunities and novel delivery strategies based on particulate systems for the …

Intranasal delivery and transfection of mRNA therapeutics in the brain using cationic liposomes

HK Dhaliwal, Y Fan, J Kim, MM Amiji - Molecular Pharmaceutics, 2020 - ACS Publications
Nucleic acid-based therapeutics, including the use of messenger RNA (mRNA) as a drug
molecule, has tremendous potential in the treatment of chronic diseases, such as age …

Oral delivery of liposomes

W Wu, Y Lu, J Qi - Therapeutic delivery, 2015 - Taylor & Francis
Ever since the invention by Bangham in 1966, liposomes has been evolving steadily not
only as a nice tool to study the function of cell membranes but also as unique drug carriers …

Vesicular systems for intranasal drug delivery

IA Alsarra, AY Hamed, FK Alanazi… - Drug delivery to the …, 2010 - Springer
Recently, the nasal route for systemic drug delivery has gained great interest. It provides
several advantages over other routes of drug administrations. These include rapid …