Bone tissue undergoes constant remodeling and healing when fracture happens, in order to
ensure its structural integrity. In order to better understand open biological and clinical …

Bone is an extremely dynamic tissue, undergoing continuous remodeling for its whole
lifetime, but its regeneration or augmentation due to bone loss or defects are not always …

Introduction• Bone biology• The relevance of cell–cell interactions in bone tissue
engineering• Co‐culture models in bone tissue engineering‐Angiogenesis‐Osteochondral …

The integrity of the skeleton is maintained by the coordinated and balanced activities of the
bone cells. Osteoclasts resorb bone, osteoblasts form bone, and osteocytes orchestrate the …

The process of bone repair has always been a natural mystery. Although bones do repair
themselves, supplemental treatment is required for the initiation of the self-regeneration …

Healthy bone is maintained by the process of bone remodeling. An unbalance in this
process can lead to pathologies such as osteoporosis which are often studied with animal …

Capturing the complexity of bone and cartilage into threedimensional in vitro models
remains one of the most important challenges in the field of the tissue engineering. Indeed …

For studying cellular processes three-dimensional (3D) in vitro models are of a high
importance. For tissue engineering approaches osseous differentiation is performed on 3D …

As the population of western societies on average ages, the number of people affected by
bone remodeling-associated diseases such as osteoporosis continues to increase. The …

In vitro evaluation of bone graft materials is generally performed by analyzing the interaction
with osteoblasts or osteoblast precursors. In vitro bone models comprising different cell …