Galanin and its receptors: a novel strategy for appetite control and obesity therapy

P Fang, M Yu, L Guo, P Bo, Z Zhang, M Shi - Peptides, 2012 - Elsevier
The rapid increase in the prevalence of overweight and obesity is becoming an important
health problem. Overweight and obesity may cause several metabolic complications …

Galanin peptide family regulation of glucose metabolism

P Fang, M Yu, M Shi, P Bo, Z Zhang - Frontiers in Neuroendocrinology, 2020 - Elsevier
Recent preclinical and clinical studies have indicated that the galanin peptide family may
regulate glucose metabolism and alleviate insulin resistance, which diminishes the …

Galanin–25 years with a multitalented neuropeptide: Galanin and the neuroendocrine axes

I Mechenthaler - Cellular and Molecular Life Sciences, 2008 - Springer
Galanin has diverse physiological functions, including nociception, arousal/sleep regulation,
cognition, and many aspects of neuroendocrine activities that are associated with feeding …

Galanin‐like peptide and the regulation of feeding behavior and energy metabolism

K Shiba, H Kageyama, F Takenoya… - The FEBS …, 2010 - Wiley Online Library
The hypothalamic neuropeptides modulate physiological activity via G protein‐coupled
receptors (GPCRs). Galanin‐like peptide (GALP) is a 60 amino acid neuropeptide that was …

Galanin peptide family as a modulating target for contribution to metabolic syndrome

P Fang, M Yu, M Shi, Z Zhang, Y Sui, L Guo… - General and comparative …, 2012 - Elsevier
Metabolic syndrome (MetS) is defined as abdominal central obesity, atherogenic
dyslipidemia, insulin resistance, glucose intolerance and hypertension. The rapid increasing …

Central nervous system regulation of food intake and energy expenditure: role of galanin-mediated feeding behavior

PH Fang, M Yu, YP Ma, J Li, YM Sui… - Neuroscience bulletin, 2011 - ncbi.nlm.nih.gov
Galanin is a neuropeptide widely expressed in the brain. It is implicated in energy
expenditure, feeding, and the regulation of body weight. Numerous studies have revealed …

Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome

NJ Poritsanos, TM Mizuno, ME Lautatzis… - International Journal of …, 2009 - nature.com
Objective: Galanin (GAL) has a role in the regulation of food intake by way of acting on the
central nervous system in rodents. High serum GAL levels have been observed in obese …

Galanin and the neuroendocrine axes

I Merchenthaler - Galanin, 2010 - Springer
Galanin has diverse physiological functions, including nociception, arousal/sleep regulation,
cognition, and many aspects of neuroendocrine activities that are associated with feeding …

Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference

AC Adams, JC Clapham, D Wynick… - Journal of …, 2008 - Wiley Online Library
It has been widely suggested that saturated fat consumption has fuelled the current obesity
epidemic. Macronutrient choices appear to be important not only as potential factors …

Galanin/GALP and galanin receptors: role in central control of feeding, body weight/obesity and reproduction?

AL Gundlach - European journal of pharmacology, 2002 - Elsevier
Scientific and commercial pharmacological interest in the role of galanin and galanin
receptors in the regulation of food intake, energy balance, and obesity has waned recently …